Summary of Gene Editing BD deals large pharma/biotech companies have engaged primarily in collaborations with innovative CRISPR companies to access the technology

About 8 percent of the human genome was “missing” from prior sequences. That’s about 200 million base pairs of DNA or roughly the length of an entire chromosome. Those gaps have now been filled in by the #T2T consortium. Latest issue of Codon 👇 buff.ly/3LV55VV

Cats have a protein, called Fel d 1, present in their saliva that can cause allergies in people. Researchers at InBio used #CRISPR to knock out the genes encoding Fel d 1 in cells taken from cats. Read more in the latest issue of Codon. buff.ly/3LV55VV

Prime editors are modified proteins that can substitute bases in DNA (like swap a C for a T). A modified version is up to 5000-times more efficient. Read more in the latest version of Codon. buff.ly/3LV55VV

About 8 percent of the human genome was “missing” from prior sequences. That’s about 200 million base pairs of DNA or roughly the length of an entire chromosome. Those gaps have now been filled in by the #T2T consortium. The latest issue of Codon 👇 buff.ly/3LV55VV

The latest issue of Science Magazine reports a complete human genome sequence! Check out the accompanying Nature Methods paper, explaining the computational assembly. buff.ly/3uPbURP

A modified #CRISPR gene-editing tool offers a more efficient way to engineer Arabidopsis plants. buff.ly/3wYYBB1

A Oxford Nanopore sequencer was used to identify possible disease-causing genomic variants in <8 hours for two patients in a hospital. #health buff.ly/38d0UpK

By modifying the #CRISPR guide RNA, researchers devised a way to correct multiple different single-nucleotide polymorphisms, in human cells, in a single experiment. buff.ly/3qF6YgY

A new review in @NAR_Open highlights the myriad tools available to design guide RNAs for #CRISPR experiments, including some that use #AI. buff.ly/3LIApqJ

A new study reveals a cleaner, more #eco-friendly way to manufacture glyphosate — the herbicide often sprayed on crops — using engineered, living cells. buff.ly/3NWISbR

A team from Yale University lay out a new method to discover metabolites, or small molecules, produced by microbes living in the human gut. buff.ly/3LJvDcB

Microbes can be engineered to produce custom-designed biomaterials, like cellulose discs that can sense environmental pollutants, or face masks that can detect the #COVID-causing virus. A new review in Nature Materials explains. buff.ly/35zVTqa

Researchers have created artificial cells that can divide their insides into distinct micro-compartments, including a synthetic nucleolus and a "storage" shell (fabriCELL) buff.ly/37c3lYW

Check out my latest article for Codon Magazine: synthetic genetic circuits assembled modularly in cooperating communities of yeast! A digest of a recent eLife - the journal paper by Carignano et al. Eric Klavins Georg Seelig Clay Wright #paperdigest #scicomm #sciencetwitter codonmag.com/p/genetic-circ…

A new article from Joa G describes a modular, plug-and-play approach to engineer coordinating communities of yeast cells. buff.ly/3J9IqTL

Fibroblast cells are programmed to turn into #heart progenitor cells, simply by bathing them in six small molecules. #health buff.ly/3KmfDgp

Yeast cells were programmed to work together using modular, genetic circuits. Those communities behaved according to simple, and predictable, mathematical equations. buff.ly/3J9IqTL

Retro Biosciences launches with $180M for anti-aging medicines and anonymous investors. And the #CRISPR patent appeal is already underway. Synthetic biology updates this week 🔻 buff.ly/3r8o1Zd

I can finally share our last work on #CRISPR for metabolic engineering just out in @naturecomms We developed a highly multiplexed, inducible system for simultaneous activation and repression of target genes. I summarise some key results below (1/6) nature.com/articles/s4146…