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Burchett et al. developed a novel 3D macrophage spheroid model to investigate how macrophages both respond to and generate mechanical forces. #cmbeYI Meenal Datta Notre Dame AME Notre Dame Engineering link.springer.com/article/10.100…

To study vascular smooth muscle cell behavior, Nagayama and Wataya developed a microgrooved substrate and found that trapping the cell nucleus in concave grooves promotes growth and differentiation. #NagayamaLab #IbarakiUniversity 【公式】茨城大学 | IBARAKI University link.springer.com/article/10.100…

Huang et al. present a comprehensive review of the current development and application of renal cancer organoids. #ChuanyuSunLab Fudan University link.springer.com/article/10.100…

Lowrey et al. present a coaxial 3D bioprinting technique to facilitate ultrasound-controlled gene delivery. #cmbeYI Carolyn Schutt Ibsen OHSU Biomedical Engineering Department link.springer.com/article/10.100…

To improve mesenchymal stem cell (MSC) culture, Heinrichs et al. reduced the population of senescent cells with dasatinib, thereby improving MSC functionality. Dr. Rebekah Margaret Samsonraj University of Arkansas link.springer.com/article/10.100…

To improve wound healing and reduce scar tissue, Sander et al. characterize ECM deposition of adipocyte-based therapeutic approaches. Ed Sander UIowa Engineering Iowa BME link.springer.com/article/10.100…

Hirway et al. developed a multicellular computation model to investigate tumor microenvironment remodeling and pre-metastatic niche formation. OhioStateBME OSUengineering The Weinberg Lab link.springer.com/article/10.100…

Silva and Jacinto review recent engineering approaches to deliver wireless light to the brain for optogenetic applications. Universidade Porto link.springer.com/article/10.100…

Xia et al. explore the damage mechanisms of endothelial networks under ultrasound cavitation. #HengyangUniversity #HuLab link.springer.com/article/10.100…

Kerivan et al. demonstrate a new approach using QCM-D for deciphering the feedback mechanisms that drive emergent cytoskeletal ensemble crosstalk and intracellular mechanosensing. Nikki Reinemann emkerivan Ole Miss Engineering link.springer.com/article/10.100…

Taufalele et al. explore the effects of substrate stiffening on endothelial epigenetics, with a focus on DNA methylation. Vanderbilt BME Cynthia Reinhart-King link.springer.com/article/10.100…

Miyano et al. study the molecular mechanisms underlying hyperosmolarity-induced autophagy, specifically looking at the effects of transcription factor EB (TFEB) and Ca2+ signaling pathways. 東京都立大学 広報担当 Tokyo University of Science (TUS) link.springer.com/article/10.100…

Seibel et al. studied the effects of obesity-associated conditions (like chronic inflammation, hypoxia, and tissue hyperlipidemia) on lymphatic draining function using 3D engineered in vitro models of lymphatic vessels. Boston University Biomedical Engineering link.springer.com/article/10.100…

Seymour et al. demonstrated the efficacy of using automated cell dispensing for high throughput screening of cervical and endometrial cancer in vitro models. Biological & Ecological Engineering link.springer.com/article/10.100…

Martinez-Zalbidea et al. created extracellular vesicles from CRISPR-dCas9 engineered mesenchymal stem cell line overexpressing TSG-6. The therapeutic effect of these vesicles was explored on in vitro human intervertebral disc cells. RIT link.springer.com/article/10.100…

Liu et al. utilize a computational model approach to study the effect of ranolazine on failing hypertrophic cardiomyopathy cardiomyocytes. Shanghai Jiao Tong University link.springer.com/article/10.100…

New CMBE Issue Alert!!! 🧪🥼🧫 February 2025, Volume 18, Issue 1 Check it out to read about new research in bioengineering like recent advances in optogenetics, 3D engineered human lymphatic vessels, and cervical/endometrial cancer screening methods! link.springer.com/journal/12195/…

New CMBE Issue Alert!!! 🧪🥼🦠 April 2025, Volume 18, Issue 2 Take a look to read about the newest advancements in cellular and molecular bioengineering research! link.springer.com/journal/12195/… Cover photo credit: J. Wang et al., 2025

April 2025 Issue: Featured Article! Guo, X., Lu, Z., Xiao, W. et al. dive into the factors that may contribute to degenerative disk diseases specifically caused by annulus fibrosus impairment. Fudan University link.springer.com/article/10.100…

April 2025 Issue: Featured Article! Shabangu et al. study the morphological and mechanical changes in endothelial cells after infection by Kaposi’s sarcoma-associated herpesvirus, revealing potential diagnostic and therapeutic methods. UCT link.springer.com/article/10.100…