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Patients with high compliance to protocol may be different and prone to do better. 👉Avoid selection bias and don't do analysis on effect of treatment compliance on outcome in nonsham-controlled trials jamanetwork.com/journals/jaman… Aarhus Uni.hospital Claus Z. Simonsen JAMA Network Open John Mandrola, MD

Outcomes Following Adherence to a Randomized Stroke Trial Protocol jamanetwork.com/journals/jaman…

This looks 👀 like a great book 📘 fadlforlag.dk/produkt/akutte…

Head of bed FLAT for LVO! Early improvement HIGHER for pts laid flat versus 30 degrees with NO signal of harm in ZODIAC trial AHAMeetings #ISC24 No benefit in functional outcome at 90d although there was a trend for improvement. Sample NOT powered for long term analysis!

#STROKE In a post hoc analysis of the RESIST trial, patients with stroke of small vessel etiology exhibited a benefit with respect to remote ischemic conditioning over sham, under a per protocol framework. #ISC24 #AHAJournals ahajrnls.org/3OA2dkJ Rolf Blauenfeldt Claus Z. Simonsen

Rolf Blauenfeldt is presenting on pre-hospital treatment 2024 INFORMS Security Conference

Last Friday, Sine Buus defended her PhD thesis regarding socieconomic inequalities in access to stroke treatment. Louise McCullough came all the way from Houston to serve as opponent! 🙏🏽

To Bypass or Not to Bypass: Triage for Suspected LVO Stroke ahajrnls.org/3x6dpzX In this #BloggingStroke post, Paul Wechsler discusses #Stroke article "Transport Strategy in Patients With Suspected Acute Large Vessel Occlusion Stroke" by Anne Behrndtz et al. Claus Z. Simonsen

🧵ICYMI: #STROKE: In a post hoc analysis of the RESIST trial, patients with stroke of small vessel etiology exhibited a benefit with respect to remote ischemic conditioning over sham, under a per protocol framework. ahajournals.org/doi/10.1161/ST… Rolf Blauenfeldt Claus Z. Simonsen

I had some thoughts… on death. We are overdue for a reconsideration of mortality vs disability in our new large core stroke world. ahajournals.org/doi/10.1161/SV…

Another large-core stroke treatment trial yielding positive results which is exciting news for the stroke community but comes with a huge responsibility on us as neurologists. Age, baseline medical conditions/functional status play a vital role but the most important factor

Sidsel Hastrup presents her study on Stroke, MI and Mortality in Type 2 diabetes. Philip Bath has some questions.

Henrik Sørensen presents at #ESOC2024 after PFO closure, patients remain in higher risk for ischemic stroke. 5/8 had an undisclosed hypercoagulable state!

EVT of PCA stroke with vs no anesthesia Anne Hertenstein C.Herweh Simon Nagel Davide Strambo Mohamad AbdalKader Marta Olivé Gadea Shadi Yaghi Volker Puetz Daniel Kaiser Liqi Shu Michele Romoli Jim Siegler, Dad, Husband, MD IL Christian H Nolte Mahmoud H. Mohammaden Isabel Fragata jnis.bmj.com/content/early/…

We followed >8000 Danes with atrial fibrillation who had a stroke and started/restarted DOAC. For incidence rates of stroke recurrence, association of recurrence with DOAC discontinuation & more, see our article in #JAMA Neurology: jamanetwork.com/journals/jaman…

Also, check out the accompanying #Editorial by Claus Z. Simonsen & Rolf Blauenfeldt. Rapid optimization of stroke systems throughout the US is needed to adapt to the increasing volume of patients who are becoming eligible for EVT under evolving practice paradigms.

New data from TENSION Study: benefits of EVT are sustained at 12 months - just published in the The Lancet Neurology! 🆕 kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2…

Just Accepted! 📰Recurrent Ischemic #Stroke/Transient Ischemic Attack After Patent Foramen Ovale Closure: A cohort study journals.sagepub.com/doi/abs/10.117… Claus Z. Simonsen

I ASSET tester vi, om semaglutid har en gavnlig effekt hos patienter med blodprop i hjernen. Studiet kører nu på Rigshospitalet og OUH, udover AUH.

🫀Cohort study of recurrent ischemic stroke/TIA after patent foramen ovale closure 🧑‍🤝‍🧑Study of 310 patients ➡️At follow up: 8 had recurrent stroke/TIA, other adverse outcomes were uncommon 🩸🩺Recurrent stroke/TIA was more frequent in those with: hypertension, hematologic