Duramax, a reinforcement learning framework designed to optimize long-term lipid-modifying therapy for CVD prevention. It helps bridge the gap between AI-driven precision and real-world clinical utility. nature.com/articles/s4174…

Our paper found #specialist outpatient clinic (#SOPC) service disruption like #COVID was associated with increased risk of #mortality and #CVD among #DM patients. Findings support #primarycare clinics are essential in public health crises. …ubs.pericles-prod.literatumonline.com/doi/10.1111/do…

In support of our previous observations, a Science Immunology study using ex vivo assays shows that dosing interval is a major factor determining the quality of T cells induced by SARS-CoV-2 mRNA and adenoviral vector vaccines science.org/doi/10.1126/sc…

Bipolar disorder affects over 40 million people worldwide. Yet diagnosis remains challenging, causing delays in effective treatment. Recent advances in understanding & emerging therapies offer hope for more precise, patient-centred care. Find out more: hubs.li/Q03GjB9W0

Read our paper on 18 Countries and HK Opioid Prescribing Trend from 2001 to 2019. Very big differences between countries and US is going down. link.springer.com/10.1007/s40263…

🔴Now live: Establishing the China–UK Cancer Prevention and Control Alliance UK and China representatives discuss establishing a China–UK Cancer Prevention and Control Alliance (CCPCA), to enhance the development and implementation of tech and advances thelancet.com/journals/lanon…

🎯 TARGET Guideline published 🎉 TARGET is a reporting guideline for observational studies of interventions that use the target trial framework. Over 3 years it was rigorously developed and was co-published today in JAMA & The BMJ doi.org/10.1001/jama.2…

Our paper found early-onset #T2DM is associated with substantially higher risks of #CKD, #renal decline, and #ESRD, reinforcing the need for targeted #prevention and #management strategies to reduce renal complications in younger T2DM patients. …ubs.pericles-prod.literatumonline.com/doi/10.1111/do…

Academics: "I have imposter syndrome" Also academics:

🥳Congrats!

Our JACC Journals paper found that #statin use for primary #prevention was associated in all-cause #mortality and major #CVD reductions with a very low risk of adverse effects among #T1DM adults, guiding personalized statin #treatment decisions in T1DM. sciencedirect.com/science/articl…

A new study reveals that 90% of liver cancer patients have at least three chronic diseases and finds a strong link between taking multiple medications and higher rates of cancer recurrence and mortality. The study has also led to a predictive model to assist doctors in creating

Our World Psychiatry (IF=65.8) World Psychiatric Association (WPA) wpanet.org Letter on a new cohort study led by Wenxin TIAN and myself CSMPR_HKU HKU Pharmacy HKU Medicine The University of Hong Kong showing a rare elevated risk of gynecologic cancers after prolactin-increasing antipsychotic use 🥂 onlinelibrary.wiley.com/doi/10.1002/wp…

Our simulation model supports the cost-effectiveness of PSA screening in China. Personalised screening based on genetic risk may provide an efficient alternative to uniform strategies by reducing unnecessary interventions for lower risk individual.sciencedirect.com/science/articl…

Our modified self-controlled case series (dx.doi.org/10.1002/pds.70…) did not identify an increased #ischemic_stroke risk with #PPI_monotherapy. However, co-prescription with #antithrombotics was associated with a higher risk. Careful monitoring is needed for them. Celine Chui HKU

Our age-specific models accurately predicted the post-acute #mortality risk within 1 year of #COVID infection, optimizing clinical strategies and resource allocation in global burden of #LongCOVID management. Published on QJM. academic.oup.com/qjmed/article/…

Happy to share that my abstract was accepted for presentation at #AES2025! As a first-time attendee and a research student doing pharmaco-epidemiological research on ASMs, I’m looking forward to presenting, learning, and connecting. See you in Atlanta this Dec😃

The TARGET 2025 guideline provides recommendations for transparent reporting of observational studies emulating a target trial to estimate causal effects, enhancing clarity and interpretation. ja.ma/4pBVasR

Our CMAJ study found a less stringent #risk threshold of 30% for intensifying #PrimaryCare encounters frequency is associated with increased overall #CVD risks and all-cause #mortality of aged 60+ #T2DM patients, but not for those below 60. cmaj.ca/content/197/32…

Congrats to Esther Chan @ CSMPR HKU and Luna Wei Yue on this excellent work on LAIA for older adults in The Lancet Psychiatry - more effective, equally safe despite extrapyramidal symptoms with 1st-generation agents (generally being replaced), not 2nd-generation! thelancet.com/journals/lanps…