We are excited to release Constant-pH Simulator to setup constant-pH simulations with various packages. We thank to Jana Shen and Anton Jansen & Pavel Buslaev for their help with AMBER and GROMACS! charmm-gui.org/input/cph youtube.com/channel/UCtHN7…

The parasites went all the way to the ANU Division of Biomedical Science & Biochemistry morning tea today! Oh my leech! 😂 It was such a warm and fun morning! #ANU🇦🇺 #Parasitology

Join John Tanner, PhD Candidate from the Corry Group, for his presentation on 4 Dec 2024 at 3pm! #BiologySeminar Details: tinyurl.com/mrrm7n5e

Tao and Corry Corry Lab ANU Division of Biomedical Science & Biochemistry investigate the binding of sodium channel inhibitors to the Naᵥ1.5 pore using simulations, revealing promiscuous, polyspecific binding at the fenestrations and central cavity. hubs.la/Q031spy70

Excited to start the year with this lovely paper with Elaine Tao showing that drugs that inhibit sodium channels bind in a range of sites within the pore cavity rather having a single distinct pose. Journal of General Physiology Science & Medicine at ANU NCI Australia

🎉 Exciting News! Our new review paper has just been published in Trends in Parasitology ! 🧠 Parasite Infections: how inflammation alters brain function Full article here: sciencedirect.com/science/articl… #Parasitology #Neuroinflammation Luísa Magalhães Lilian Lacerda Bueno - PhD Ricardo_Fujiwara

I'm so excited to have been part of this very fun collaboration with the Zhang lab! 💻💙 Please check out our preprint on this beautiful channel-like protein called XPR1 here at biorxiv.org/content/10.110…

Big congratulations to Ruitao Jin 金瑞涛 for winning an Anders Early Career Award at Lorne Proteins #lorneproteins2025 ! Presenting his work on the lipid lined pore of the OSCA mechanosensitive channel.

hey so can you email me in a happier tone i’m extremely sensitive rn and close to shedding tears

Big congratulations to the very sharp Elaine Tao who submitted her PhD last week! Our greatest Nav channel expert is rumoured to be joining the dark side of Kv. #drtao #phdone ourANU Science & Medicine at ANU 🔪🎆👩‍🔬👩‍🎓

Thrilled to share our latest preprint from YC Lin 🧪👩🏻‍💻 & Ciara Wallis showing AF2-Multimer and AF3 can quickly & accurately predict the oligomeric states & structures of proteins (& maybe can identify multiple biologically relevant oligomeric states 👀) tiny.cc/oligomers

1/ In my final project as part of the Corry Lab, we show the bacterial TAM complex facilitates the spontaneous flow of phospholipids from the IM to the OM in MD simulations.. biorxiv.org/content/10.110…

2/ ... discuss possible ways that lipids can be offloaded at the OM and use AF3 and MD data to suggest that other members of the AsmA-like protein family can accommodate lipids in their hydrophobic grooves

3/ it feels significant to be writing this as i await my flight to be transported from the inner membrane (Canberra) I've called home for the last 8 years to the outer membrane (Beijing) of my next scientific adventure

Bittersweet to announce YC's final work in our lab. We are so proud of everything she's accomplished (incl. this beautiful study showing how the TAM complex facilitates lipid flow between the bacterial inner & outer membranes). We can't wait to see what you do next, Dr. Lin 🤩

Also bittersweet to announce the final work of Elaine Tao in our lab, using AF2 to study conformational transitions in 32 voltage-gated channel superfamily members 🤩 we're so excited to watch you Nav-igate the next steps of your career, Dr. Tao 🎩 tiny.cc/VSD-AF2

Excited to share John Tanner's new work in Nat Coms! We demonstrate how PfCRT, a polyspecific peptide transporter, turns into a drug transporter for antimalarials like chloroquine and why this causes a fitness cost for the malaria parasite (1/2) tiny.cc/PfCRT

We show where chloroquine and peptides bind and help explain the polyspecific transport mechanism. (2/2)

🌟We are hiring! Seeking a postdoc to use molecular dynamics and AI to understand how ion channels are regulated by membrane lipids🌟 Join us at ourANU with amazing collaborators and great working conditions! Apply: tiny.cc/corry. Us: karri.anu.edu.au

Applications for this position close tomorrow. Don't miss out!