Many folks over the past few years have kindly asked about how to cite my `bit` package (github.com/AstrobioMike/b…), a kluge of helper scripts I add to as needed. As of last month, it's in f1000 (f1000research.com/articles/11-12…), so if it helps and you’re inclined to cite it, please do 🙂

Here, Sanchita Bhadra (UT Austin) et al describe methods for low-cost, on-site production of commonly used molecular biology reagents, with minimal instrumentation & expertise, and without the need for protein purification. ➡️…rentprotocols.onlinelibrary.wiley.com/doi/10.1002/cp…

Bringing Oxford Nanopore into my PHD lab, have to love 65kb+ reads 9 mins in at Phred scores of 23-24 (~99.6% accuracy).

Whokaryote: distinguishing eukaryotic and prokaryotic contigs in metagenomes based on gene structure microbiologyresearch.org/content/journa…

This is how the MAP-G (a pan-genomics graph data structured/algorithms that I am working on) looks like for the 273 genes that are hard to resolve identified by this work nature.com/articles/s4158… with Genome in a Bottle and Fritz Sedlazeck

“Already, the United States claims the highest rate of maternal and infant mortality among wealthy nations. Should the court overturn Roe v. Wade, these grim statistics will only get worse,” argued a Nature editorial last month go.nature.com/3QNIrli

Verkko integrates "ultra-long reads" & "long, accurate reads" to generate high-quality, #T2T human genome assemblies. ‘Running Verkko on the HG002 human genome resulted in 20 of 46 diploid chromosomes assembled without gaps at 99.9997% accuracy.’ Read: bit.ly/3ueZwLh

How to start a presentation? Most people start with all the boring info (e.g., repeating everything your host just said) and unmotivated technical details. 🥱 After a few mins, everyone starts checking their phone! 😱 How to avoid this? Here is a simple template. 🧵

A new E.coli strain is designed with an amino-acid swapped genetic code, making it resistant to viruses and also unable to replicate outside of a lab setting, preventing unwanted gene flow. #NBThighlight bit.ly/3JExOjf

Full-length, unfolded proteins are slowly translocated through nanopores without enzymes and fingerprinted go.nature.com/3GSw8RG

HI Friends, Here is a tutorial that shows you how to get the #mapping statistics of an alignment record(bam or sam) using samtools youtu.be/NRqQvAOG_YE #Bioinformatics #DataScience Samtools Team #linux #Genomics

NCBI just released the count matrices for thousands of RNA-Seq 🧬 experiments on GEO 🎉 an amazing resource 🤩 #RNASeq #Transcriptomics #Bioinformatics #OpenScience #OpenData ncbiinsights.ncbi.nlm.nih.gov/2023/04/19/hum…

Honored to have been chosen by NASA to leverage the microbes of Earth's extreme environments for plant growth in lunar regolith (soil). A superb proposal built by Braden Tierney, James Henriksen, The Two Frontiers Project, Rob Ferl, Christie Peebles, & george church science.nasa.gov/science-resear…

Wonderful talk from Daniel Lusk!😊 #TAGC24 Building synthetic chromosomes from natural DNA | Nature Communications nature.com/articles/s4146…

Congrats to Alessandro and the rest of the lab on being in the Nature Communications top 25 life and biological sciences articles of 2023 #NCOMTop25 doi.org/10.1038/s41467…

New paper from our lab on genome-scale analysis of interactions between genetic perturbations and natural genetic variants. Congrats on the nice work, Joe! Great collaboration with the Sasha Levy and Lars Steinmetz labs. nature.com/articles/s4146…

Sniffles2 detects mosaic structural variation from bulk long-read sequencing data go.nature.com/3RFnt9H rdcu.be/dXH25