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Check out this cool paper by Chase Amos from De Camilli Lab showing that the lipid transfer protein VPS13A localizes to ER-PM contacts of red blood cells when they start getting rid of their internal membranes! biorxiv.org/content/10.110…

Our new preprint reveals that the interaction of the bridge-like lipid transport protein VPS13A with the lipid scramblase XK at ER-plasma membrane contacts in K562 cells correlates with erythroid differentiation Chase Amos Yale Cell Biology Yale Neuroscience biorxiv.org/content/10.110…

This #EM_Monday I want to put the word out that I will be on job market this year! As you might have noticed, I am fascinated by the shapes of various organelles that become drastically different in specialized cells. And I want to know how and why?! The most notable…(1/5)

My work on the role of cilia in dopaminergic neurons and #Parkinsons is online now: biorxiv.org/content/10.110…; second work from my postdoc!

Mutations in LRRK2 are likely causative of Parkinson's Disease but LRRK2's function remains elusive. Exciting new work from Xinbo Wang from De Camilli Lab show a remarkable membrane remodeling activity! pnas.org/doi/10.1073/pn…

How do #organelles acquire #membrane #lipids? Our review in Annual Reviews of Cell and Dev Biology defines a family of bridge-like lipid transport proteins that control membrane area and so much more! Final version below De Camilli Lab Yale Cell Biology Andrés Guillén Samander annualreviews.org/doi/10.1146/an…

Fantastic work from Berrak Ugur revealing the unique localization of the #membrane #lipid channeling protein VPS13B

Wonderful new work from Chase Amos & Peng Xu on VPS13A during erythroid differentiation! De Camilli Lab Yale Cell Biology journals.sagepub.com/doi/10.1177/25…

We have new research from the De Camilli group De Camilli Lab replicating the pathophysiology of VPS13A in a disease-relevant cell type journals.sagepub.com/doi/10.1177/25… VPS13A interacts with XK at the plasma membrane of cells after erythroid differentiation Chase Amos Yale Cell Biology Yale Neuroscience

This week’s #TraineeTuesday ⭐️ is Chase Amos, a Yale Interdepartmental Neuroscience Program graduate student mentored by Pietro De Camilli! He recently published two papers 🥳 Let’s dive into his research journey! [1/5]

My new paper is now on BioRxiv 🎉🎉🎉🎉 twittorial to come 😊 Ectopic Reconstitution of a Spine-Apparatus Like Structure Provides Insight into Mechanisms Underlying Its Formation biorxiv.org/content/10.110…

.Berrak Ugur et al De Camilli Lab Yale Cell Biology Yale Neuroscience characterize the bridge-like lipid transfer protein VPS13B & report its localization btwn #Golgi cisternae & its impact on Golgi complex reformation after BFA-induced dispersion. hubs.la/Q02Rm3lt0 Florian Schueder @MLeonzino

Excited to share our latest preprint, now available on bioRxiv! biorxiv.org/content/10.110… #YaleCellBio #YaleNeuro #PDClab #Lysosome

Excited to share our work in Journal of Cell Biology! Huge thanks to everyone who contributed. Discovering this lipid transport protein localized between Golgi cisternae was a fascinating and unexpected finding! 👀 #CellBiology #Golgi #LipidTransport De Camilli Lab

Our paper is out in time for #EM_Monday! It is about a specialized neuron-specific ER, the spine apparatus, that is close to synapses and has a peculiar shape. If you think neurons are special, the spine apparatus is their🦄horn! But how does it form?!(1/9)doi.org/10.1016/j.cub.…

Cell membranes sustain phospholipid imbalance via cholesterol asymmetry: Cell cell.com/cell/fulltext/…

BLTP3A is associated with membranes of the late endocytic pathway and is an effector of CASM biorxiv.org/content/10.110…

biorxiv.org/content/10.110… This work was completed at De Camilli Lab Yale Neuroscience Yale Cell Biology with incredible colaborators Rubia Mancuso, Marianna Leonzino, Caroline Zeiss, Diane Krause with generous supports from Aligning Science Across Parkinson’s NIH.

Anbang Dai, Pietro De Camilli et al. report the localization of BLTP2 in different human cell types & reveal binding partners that mediate its tethering to the PM & to PM-connected structures including certain #endosomes & #macropinosomes undergoing fusion hubs.la/Q03GK4ff0