Charles Dariane (@charlesdariane) 's Twitter Profile
Charles Dariane

@charlesdariane

MD PhD Urologist Surgeon Assistant Professor, GenitoUrinary Oncology #ProstateCancer @HopitalPompidou, U1151 @NeckerInem Paris 🇫🇷. Former Research fellow 🇨🇦

ID: 3107391549

calendar_today23-03-2015 11:18:15

5,5K Tweet

1,1K Followers

354 Following

Association Française d'Urologie - AFU (@afurologie) 's Twitter Profile Photo

Vous êtes cycliste amateur et prendrez part à notre ascension du mont Ventoux le 30 août ? 🚵🏼 Retrouvez quelques conseils pour bien vous préparer. ️Et n'oubliez pas❗Il est possible de faire l'ascension en vélo électrique. Avec le parrainage de Ministère des Sports 🇫🇷 et Ministère de la Santé et de l'Accès aux soins

Vous êtes cycliste amateur et prendrez part à notre ascension du mont Ventoux le 30 août ? 🚵🏼 Retrouvez quelques conseils pour bien vous préparer.

️Et n'oubliez pas❗Il est possible de faire l'ascension en vélo électrique.

Avec le parrainage de <a href="/Sports_gouv/">Ministère des Sports 🇫🇷</a> et <a href="/Sante_Gouv/">Ministère de la Santé et de l'Accès aux soins</a>
Tyler Seibert MD PhD (@tylersbrt) 's Twitter Profile Photo

6/ We included 799 pts on modern, MRI-driven AS across 3 centers Two 🔑 features explain nearly all risk of AS failure in multivar analysis: 1️⃣ cribriform morphology → HR 13‼️ 2️⃣ PI-RADS 3-5 → HR 5

6/

We included 799 pts on modern, MRI-driven AS across 3 centers

Two 🔑 features explain nearly all risk of AS failure in multivar analysis:

1️⃣ cribriform morphology → HR 13‼️

2️⃣ PI-RADS 3-5 → HR 5
Tyler Seibert MD PhD (@tylersbrt) 's Twitter Profile Photo

7/ 📝Summary ✅ AS *very safe* for all GG1 ✅ AS *very safe* for MRI-invisible GG2 non-cribriform ❌❌ Cribriform → do not offer AS ☑️ MRI-visible, non-cribriform GG2 → AS safe but 🤔could benefit from ⬆AS intensity?

7/

📝Summary

✅ AS *very safe* for all GG1 

✅ AS *very safe* for MRI-invisible GG2 non-cribriform

❌❌ Cribriform → do not offer AS

☑️ MRI-visible, non-cribriform GG2 → AS safe but 🤔could benefit from ⬆AS intensity?
Eric Barret (@barret_e) 's Twitter Profile Photo

Irreversible Electroporation in Patients with Intermediate-risk Prostate Cancer: a safe and effective treatment option - Results from the PRESERVE Trial - sciencedirect.com/science/articl…

Yüksel Ürün (@dryukselurun) 's Twitter Profile Photo

STAMPEDE: ADT leads to high fracture rates in prostate cancer, esp. with mets. Zoledronic acid lowers fracture risk in metastatic, not non-metastatic. Should we add ZA or Deno in bone protecting dose? #prostatecancer #Oncology Annals of Oncology Advanced Prostate Cancer Consensus Conference OncoAlert

STAMPEDE: ADT leads to high fracture rates in prostate cancer, esp. with mets. 
Zoledronic acid lowers fracture risk in metastatic, not non-metastatic.
Should we add ZA or Deno in bone protecting dose?
#prostatecancer #Oncology 
<a href="/Annals_Oncology/">Annals of Oncology</a> <a href="/APCCC_Lugano/">Advanced Prostate Cancer Consensus Conference</a> <a href="/OncoAlert/">OncoAlert</a>
International Society of Urological Pathology (@intsocuropath) 's Twitter Profile Photo

#ISUP Upcoming Event 2025 ISUP Vienna Multidisciplinary Consensus Conference on Evaluation of Treatment Effects in Prostate and Bladder Cancer #ISUPVienna2025 🇦🇹 📅 11 Sept 2025, immediately following European Society of Pathology (ESP) #ECPCongress Register here: ISUP-VIENNA-2025.eventbrite.com

#ISUP Upcoming Event

2025 ISUP Vienna Multidisciplinary Consensus Conference on Evaluation of Treatment Effects in Prostate and Bladder Cancer #ISUPVienna2025 🇦🇹 

📅 11 Sept 2025, immediately following <a href="/ESP_Pathology/">European Society of Pathology (ESP)</a> #ECPCongress 

Register here: 
ISUP-VIENNA-2025.eventbrite.com
Matt Nielsen, MD (@m_e_nielsen) 's Twitter Profile Photo

Nice work from Monda et al documenting >5x 📉↘️ surgical overtreatment of low risk prostate cancer in SEER-Medicare & MUSIC Urology ✅uncoupling dx from rx ✅reframes context of benefit/harm assoc w PSA screening 👀➡️ jamanetwork.com/journals/jamao…

Nice work from Monda et al documenting &gt;5x 📉↘️ surgical overtreatment of low risk prostate cancer in SEER-Medicare &amp; <a href="/MUSICUrology/">MUSIC Urology</a> 

✅uncoupling dx from rx
✅reframes context of benefit/harm assoc w PSA screening

👀➡️ jamanetwork.com/journals/jamao…
Emre Yekedüz (@yekeduz_emre) 's Twitter Profile Photo

🚨A must-read review in NatureRevClinOncol ➡️EMT and cancer: what clinicians should know 🎯Cancer cell plasticity fuels metastasis & treatment resistance. OncoAlert Yüksel Ürün #cancer #Oncology #MedX 👉doi.org/10.1038/s41571…

🚨A must-read review in <a href="/NatRevClinOncol/">NatureRevClinOncol</a> ➡️EMT and cancer: what clinicians should know

🎯Cancer cell plasticity fuels metastasis &amp; treatment resistance.

<a href="/OncoAlert/">OncoAlert</a> <a href="/DrYukselUrun/">Yüksel Ürün</a> #cancer #Oncology #MedX

👉doi.org/10.1038/s41571…
Jonathan Olivier (@jo_olivier85) 's Twitter Profile Photo

Thrilled to share our new BJU International study! 📊 Quantifying Gleason pattern 4 via MRI & targeted biopsy predicts prostate cancer metastasis better than standard Gleason grading & risk scores. Precision matters in risk stratification. 🔗 doi.org/10.1111/bju.16… Andrew Vickers

Andrew Vickers (@vickersbiostats) 's Twitter Profile Photo

When an RCT and an observational study have virtually identical results, you can be a little more definitive: ePLND offers zero biochemical recurrence benefits but does reduce metastasis

NEJM (@nejm) 's Twitter Profile Photo

𝗠𝗲𝗰𝗵𝗮𝗻𝗶𝘀𝗺𝘀 𝗼𝗳 𝗔𝗰𝘁𝗶𝗼𝗻 𝗼𝗳 𝗧𝗲𝘀𝘁𝗼𝘀𝘁𝗲𝗿𝗼𝗻𝗲 Many of the benefits and some of the risks of testosterone treatment are mediated by the mechanisms through which testosterone acts. Testosterone has anabolic effects on muscle (panel A) and bone (panel B) and

𝗠𝗲𝗰𝗵𝗮𝗻𝗶𝘀𝗺𝘀 𝗼𝗳 𝗔𝗰𝘁𝗶𝗼𝗻 𝗼𝗳 𝗧𝗲𝘀𝘁𝗼𝘀𝘁𝗲𝗿𝗼𝗻𝗲 

Many of the benefits and some of the risks of testosterone treatment are mediated by the mechanisms through which testosterone acts. Testosterone has anabolic effects on muscle (panel A) and bone (panel B) and
Adam B. Weiner, MD (@adam_weiner535) 's Twitter Profile Photo

🚨Prostatitis: A review🚨 💡Prostatitis, especially the chronic forms, can be some of the toughest things to treat. 📙Excellent update in JAMA on the latest approaches 👏 Minh Pham, MD Urology@UNC NM Urology 🔗shorturl.at/U8RRA

🚨Prostatitis: A review🚨

💡Prostatitis, especially the chronic forms, can be some of the toughest things to treat.

📙Excellent update in <a href="/JAMA_current/">JAMA</a> on the latest approaches

👏 Minh Pham, MD <a href="/UNCurology/">Urology@UNC</a> <a href="/NM_Urology/">NM Urology</a> 

🔗shorturl.at/U8RRA
MedinaPolo (@jmedinapolo) 's Twitter Profile Photo

Happy to share the Systematic Review and Meta-analysis Infectious Complications After Transrectal Versus Transperineal Prostate Biopsy led by Fabian Stangl ESIU - EAU Section of Infections in Urology Eur Urol Focus Available on sciencedirect.com/science/articl…

Happy to share the Systematic Review and Meta-analysis Infectious Complications After Transrectal Versus Transperineal Prostate Biopsy led by <a href="/StanglFabian/">Fabian Stangl</a> <a href="/ESIUeau/">ESIU - EAU Section of Infections in Urology</a> <a href="/EurUrolFocus/">Eur Urol Focus</a> Available on sciencedirect.com/science/articl…
European Urology (@euplatinum) 's Twitter Profile Photo

📢 MRI-led active surveillance for #ProstateCancer in 1150 men: 🧠 2 in 3 avoided biopsy at 5y 📉 91% EFS in MRI-invisible Gleason 3+3 ⚠️ Only 5% progressed to ≥Gleason 4+3 📚 Published in European Urology 🔗buff.ly/elyj2IG #UroTwitter #MRI #Urology #PCa

📢 MRI-led active surveillance for #ProstateCancer in 1150 men:
🧠 2 in 3 avoided biopsy at 5y
📉 91% EFS in MRI-invisible Gleason 3+3
⚠️ Only 5% progressed to ≥Gleason 4+3
📚 Published in European Urology
🔗buff.ly/elyj2IG 
#UroTwitter #MRI #Urology #PCa
Neeraj Agarwal, MD, FASCO (@neerajaiims) 's Twitter Profile Photo

Just in JAMA Network Open 👉 In pt level data from two ph3 trials (n=2187) 👉statin use associated with ⬆️ OS in advanced #prostatecancer treated with apalutamide. Congrats Zeynep Irem Ozay, MD and Soumyajit Roy (Soum) Free access👉 bit.ly/3HI1ZYJ Prostate Cancer Foundation UroToday.com OncoAlert

Just in <a href="/JAMANetworkOpen/">JAMA Network Open</a> 👉 In pt level data from two ph3 trials (n=2187) 👉statin use associated with ⬆️ OS in advanced #prostatecancer treated with apalutamide. Congrats <a href="/ziremozay/">Zeynep Irem Ozay, MD</a> and <a href="/Soum_Roy_RadOnc/">Soumyajit Roy (Soum)</a> Free access👉 bit.ly/3HI1ZYJ <a href="/PCFnews/">Prostate Cancer Foundation</a> <a href="/urotoday/">UroToday.com</a>  <a href="/OncoAlert/">OncoAlert</a>
𝙳𝚊𝚟𝚒𝚍 𝙲𝚊𝚗𝚎𝚜 (@canesdavid) 's Twitter Profile Photo

I'm amazed how often prostate size is known, and PSA density is never calculated or discussed even once. Patient subjected to numerous biopsies for PSA "spikes" that are perfectly explainable by a zero cost calculator test.

Laura Bukavina (@laurabukavinamd) 's Twitter Profile Photo

Great summary of TURBT complications just in time for #ibcg25 and surgical toxicity of Turbt ⬇️ 📊 72,284 TURBT, 43.5% had a complication within 30 days ➡️ Mostly minor (Clavien I–II: UTI 9%, retention 8%, irritative sx 7.6%) 💀 Major events rare (Clavien IV–V: <1%, death 1.9%)

Great summary of TURBT complications just in time for #ibcg25 and surgical toxicity of Turbt ⬇️ 
📊 72,284 TURBT, 43.5% had a complication within 30 days
➡️ Mostly minor (Clavien I–II: UTI 9%, retention 8%, irritative sx 7.6%)
💀 Major events rare (Clavien IV–V: &lt;1%, death 1.9%)
Yüksel Ürün (@dryukselurun) 's Twitter Profile Photo

New review in European Urology: 🌱Plant-based, Mediterranean & low-inflammatory diets are linked with lower prostate cancer progression & mortality. 🍔Western & ultra-processed diets increase risks. #ProstateCancer #Oncology #Prevention European Urology Prostate Cancer Foundation Advanced Prostate Cancer Consensus Conference

New review in European Urology:
🌱Plant-based, Mediterranean &amp; low-inflammatory diets are linked with lower prostate cancer progression &amp; mortality.
🍔Western &amp; ultra-processed diets increase risks.
#ProstateCancer #Oncology #Prevention
<a href="/EUplatinum/">European Urology</a> <a href="/PCFnews/">Prostate Cancer Foundation</a> <a href="/APCCC_Lugano/">Advanced Prostate Cancer Consensus Conference</a>