📢 Applications are now open for the seventh installment of our Fluorescent Proteins and Biological Sensors conference, showcasing the development of cutting-edge tools & technology for biological imaging. Learn more and apply by June 9 ➡️janelia.org/you-janelia/co… Janelia Conferences

LOV-Turbo is published today in Nature Methods and plasmids for LOV-Turbo are available on Addgene, here: addgene.org/browse/article… We hope many people will use LOV-Turbo in exciting new ways! nature.com/articles/s4159… If you plan to use NanoLuc BRET to activate LOV-Turbo, please

Our work about superPLD is now published! In this paper, we describe how we can harness mammalian cell-based directed evolution to engineer a membrane editor (phospholipase D; PLD) with superior performance in mammalian cells. 1/n nature.com/articles/s4155…

2 funded PhD position available at Institut de Biologie Structurale to work on fluorescent protein research, combining single molecule imaging, NMR and x-ray crystallography

TransitID is out today in Cell! This is a proximity labeling method for unbiased discovery of endogenous proteins that traffick from a defined “source” location to a defined “destination” location. TransitID uses sequential labeling by TurboID in the source, followed by a chase

So happy to see our paper on Talin Shock Absorbing Materials (TSAMs) out today in Nature Nanotechnology. The protein Talin has amazing mechanical properties. Jennifer Hiscock and me harnessed them to make a new material that can catch supersonic projectiles nature.com/articles/s4156…

Excited to share our research in Nature Chemical Biology ! We developed a bacterial orthogonal DNA replication system (BacORep) and equiped it with an engineered error-prone orthogonal DNA polymerase. OrthoRep, you just got a new friend :) 👉 nature.com/articles/s4158…

nature.com/articles/s4159…

Improving split reporters of protein-protein interactions through orthology-based protein engineering | bioRxiv biorxiv.org/content/10.110…

📗#Publication | "Engineering paralog-specific PSD-95 recombinant binders as minimally interfering multimodal probes for advanced #imaging techniques" eLife - the journal by Matthieu Sainlos It presents an original way of specifically labelling endogenous #PSD95🔬🧠 elifesciences.org/articles/69620

Happy to see this paper out. A fantastic tool for every scientist interested in labelling PSD-95 to study synapses. Full characterization of this tool available on addgene ;) Congrats Matthieu Sainlos and everyone who help with this (big high five to Charlotte)

Exciting news for #RICT2024 ! Speakers and topics for the 58th International Conference on Medicinal Chemistry organized by Société de Chimie Thérapeutique are online! 🌐Join us in #Bordeaux, July 3-5, 2024. 🗓️Abstracts & early bird registration deadline: May 14. 🔗More at rict2024.org

Excited to share our work on peptide-based covalent inhibitors designed to target a conserved histidine on the bacterial sliding clamp. See also our two X-ray structures of the covalent adducts. Nice collaboration with Dominique and Jérôme CNRS 🌍 - . doi.org/10.1021/jacsau…

🔬Ever wanted to spy on your model system? 🕵️‍♂️ Now you can! With bio-orthogonal chemical labeling, we've unlocked the ability to capture transient cellular events. 🌟 Dive in our study in Science Magazine: science.org/doi/10.1126/sc… A 🧵 1/15

In our newest practical guide, developed with Google DeepMind and EMBL-EBI, delve into the fundamentals of #AlphaFold, explore its strengths and limitations, and gain practical skills through hands-on exercises. Start the free, self-paced tutorial today: ebi.ac.uk/training/onlin…

#IINSgrant🚀 Manon Darribère received Fondation pour la Recherche Médicale grant! Thesis: Directed protein evolution for the development of protein-protein interactions stabilizers – Application to the investigation of molecular mechanism involved in synaptic transmission and new therapeutic strategie

The Herten lab presents Protein-tag degree of labeling (ProDOL) , a versatile reference-based approach for experimentally determining the degree of target labeling for quantitative microscopy. nature.com/articles/s4159…

Join us next Thursday, November 13th, at the IECB amphitheater for our annual Chemistry & Biology Interface Day covering the hottest research topics at our beautiful Nouvelle Aquitaine Region 🤩 🧪 ⚗️ 🧫 🦠 🔬 🤓 !!! Special guest: Dr Priya Ramakrishna from the EPFL, Lausanne