With PhD admissions season in full swing I'm reposting the application writing guide James Fraser (A$AP J) and I wrote. We discuss an insider view+advice on quantitative biology PhD program admissions having both served on admissions committees. hershbhargava.com/writing/applyi…

An engineered T cell (center) is designed to deliver therapies to the brain. This T cell displays orange synthetic receptors on its surface, which recognize components of extracellular matrix fibers that are only found in the brain. Within the cell, downstream signaling pathways

We explored exciting new directions for cell engineering Cell Design Institute @UCSF out now in Science: 🎯 Synthetic immune cells that suppress inflammation in targeted tissues. doi.org/10.1126/scienc… 🧠 Tissue-sensing cells that deliver therapies to the brain. doi.org/10.1126/scienc… 🧵⬇️

Check out our latest work on building “smart cells” with a tissue GPS to precisely treat some of the most challenging diseases without off-target toxicity. Brain targeting: science.org/doi/10.1126/sc… T cells with new immunosuppressive functions: science.org/doi/10.1126/sc…

Bravo to Wendell Lim, PhD, and team for making the cover of Science Magazine! The team armed immune cells with “molecular GPS” to find and treat brain cancer, MS and type I diabetes. Clinical trials could begin as soon as 2025. Cell Design Institute @UCSF ARPA-H National Cancer Institute tiny.ucsf.edu/BeJ9N2

HUGE congratulations to my labmates Nish Reddy and DrMilosSimic!! Making waves so big we almost had a tsunami today 🌊

Thrilled to share our latest collaborative work with the Lim Lab, it has been an incredible journey that wouldn’t have been possible without the creativity and dedication of everyone. THANKS TO THE TEAMS Nish Reddy Cell Design Institute @UCSF Hebrok Lab Audrey Parent @lillian_xyn Diabetes Center at UCSF et al 🎉

.UC San Francisco scientists have developed a “molecular GPS” system that makes it so that T cells can target and attack brain tumor cells without harming healthy tissue: buff.ly/41gMxu0 buff.ly/4fSD40p Okada Lab @ UCSF Cell Design Institute @UCSF DrMilosSimic UCSF Helen Diller Family Comprehensive Cancer Ctr Science Magazine

Congratulations Toshi and Coralie!

New from Drs. Nish Reddy, Wendell Lim, and others at Cell Design Institute @UCSF! They engineered human T cells to make a synthetic receptor recognizing overactive T cells that can #AutoimmuneDisease and #OrganRejection. 📃Science Magazine: bit.ly/3ZLzWwA 🎧: bit.ly/3BCg72H

Congratulations Adam!!

Please RT! We are hiring Junior Specialists (pre-PhD level) for variety of cell engineering and synthetic biology projects. Our trainees have gone on to PhD, MD, and industry positions at UC San Francisco, Harvard University, Sonoma Biotherapeutics, Genentech, ArsenalBio, UC San Diego, etc! aprecruit.ucsf.edu/JPF05588