Muito orgulhosa pelo destaque do nosso recente artigo científico do CCavadas Lab no jornal Público !! #progeria #aging #senescence Progeria #ghrelin onlinelibrary.wiley.com/doi/full/10.11… Center for Neuroscience and Cell Biology Universidade de Coimbra #womeninscience

“Ghrelin administration rescues molecular and histopathological progeroid features, prevents progressive weight loss in later stages, reverses the lipodystrophic phenotype, and extends lifespan of #Progeria mice”. Congrats Cláudia Cavadas & C Aveleira!👏 onlinelibrary.wiley.com/doi/10.1111/ac…

We are #hiring!👋 Five research fellowship positions are currently available to work in the #CInTech project focused on #mRNA based formulations for therapeutics. 🗓️27/02/24 👉apply.uc.pt/IT137-24-77 Center for Neuroscience and Cell Biology Universidade de Coimbra

Our lab is committed to better understand the pathology, new models, therapies for 3 rare diseases: ➡️ Hutchinson-Gilford Progeria Syndrome ➡️ Machado-Joseph Disease ➡️Familiar Fatal Insomnia Center for Neuroscience and Cell Biology Universidade de Coimbra #RareDiseaseDay #lightupforrare🟪🟦🟩

On 4th April, Claudia Cavadas, Associate Professor, Faculty of Pharmacy at University of Coimbra, will be talking about: Neuroendocrine strategies to tackle ageing #longevity #ageing #research Cláudia Cavadas More details about this and future webinars: bsra.org.uk/events/seminar…

Isabel Santana presenting a long career in neurology and sharing the knowledge about prion diseases at our advanced course “ Unveiling the Secrets of Circadian Rhythm & Sleep” Center for Neuroscience and Cell Biology #priondiseases

Starting the second day of “Unveiling the Secrets of Circadian Rhythm & Sleep” advanced course organized by CCavadas Lab Center for Neuroscience and Cell Biology Institute of Interdisciplinary Research Universidade de Coimbra #sleep #circadianrhythm #aging

Joaquin Castilla presenting the open seminar about Fatal Familial Insomnia Center for Neuroscience and Cell Biology CIC bioGUNE

Now the neurologist João Durāes presenting the link between Neurodegenerative Disorders and circadian rhythm. Center for Neuroscience and Cell Biology FMUC - Faculdade de Medicina da U Coimbra

Excellent conference by Olga Barca CiMUS about “Metabolic tempo: deciphering astrocyte clock entrainment via Insulin and AMPK signaling pathways” at our advanced course “Unveiling the Secret of Circadian Rhythm & Sleep in Health and Disease” Center for Neuroscience and Cell Biology Universidade de Coimbra Institute of Interdisciplinary Research

We were at the 9th European Congress of Pharmacology #Ephar2024 Center for Neuroscience and Cell Biology Universidade de Coimbra

We were at #EuropeanResearchersNight in Coimbra Center for Neuroscience and Cell Biology Institute of Interdisciplinary Research Universidade de Coimbra

Our last paper published in Aging Cell!!! Transplantation of senescent cells in the skin accelerate ageing of other parts of the body, namely the brain!! doi.org/10.1111/acel.1… #aging #senescence #cognition #skin Center for Neuroscience and Cell Biology Universidade de Coimbra @Passoslab

We are organizing an advanced course for PhD students Center for Neuroscience and Cell Biology “Advanced Insights into Primary Cilia: Molecular Functions, Disease Mechanisms, and Ageing” 7-8 November. Information about the speakers cnc.uc.pt/en/pdbeb/beb-a…

We are starting our symposium!!

Overlooked histories in ageing research: Pioneering women at the foundation of our field onlinelibrary.wiley.com/doi/full/10.11…

Our results support the concept that the accumulation of senescent cells in the skin can exert #aging effects on other organs including the brain. onlinelibrary.wiley.com/doi/10.1111/ac… CCavadas Lab @PassosLab Center for Neuroscience and Cell Biology

In our last paper we show that Circadian rhythms are disrupted in patients and preclinical models of Machado-Joseph disease #circadianrhythm #brain #MachadoJosephDisease doi.org/10.1093/brain/…

Ribeiro et al. show that rest-activity cycles, light re-entrainment and core body temperature regulation are impaired in Machado-Joseph disease, with the underlying mechanisms including disruptions in essential neuropeptides of the central clock. tinyurl.com/ykscwp9r