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Skeletal muscle energetics explain the sex disparity in mobility impairment in the Study of Muscle, Mobility and Aging (SOMMA) 👉Women had lower muscle mitochondrial energetics compared to men, which largely explain their greater odds of lower-extremity mobility impairment.

Calling all medical students - aging research needs you! Apply now for UCSF 2024 MSTAR summer research program. Learn from all-star mentors how to solve the most meaningful and complex problems facing society. Apps open now, due Feb 16. #Geriatrics #Aging geriatrics.ucsf.edu/education/medi…

Percutaneous biopsies of skeletal muscle and adipose tissue in individuals older than 70: methods and outcomes in t… pubmed.ncbi.nlm.nih.gov/38315316/ The Study of Muscle, Mobility and Aging's experience based on 861 biopsies.

Energetics and clinical factors for the time required to walk 400 m: The Study of Muscle, Mobility and Aging (SOMMA) pubmed.ncbi.nlm.nih.gov/38243364/ New and established correlates of walking speed.

Signatures of cysteine oxidation on muscle structural and contractile proteins are associated with physical performance and muscle function in older adults: Study of Muscle, Mobility and Aging (SOMMA) - Day - Aging Cell - Wiley Online Library onlinelibrary.wiley.com/doi/10.1111/ac…

Associations of accelerometry-measured and self-reported physical activity and sedentary behavior with skeletal mus… pubmed.ncbi.nlm.nih.gov/38341136/ SOMMA Result - Muscle tissue mito function reflects physical activity patterns

Signatures of cysteine oxidation on muscle structural and contractile proteins are associated with physical perform… pubmed.ncbi.nlm.nih.gov/38332629/ SOMMA Study Result: Potentially reversible muscle protein oxidation associated with poorer performance

Associations between D3Cr muscle mass and MR thigh muscle volume with strength, power, physical performance, fitness, and limitations … pubmed.ncbi.nlm.nih.gov/38367212/ New from SOMMA - associations tend to be stronger in men than in women.

Lower muscle mitochondrial energetics is associated with greater phenotypic frailty in older women and men: the Study of Muscle, Mobility and Aging pubmed.ncbi.nlm.nih.gov/37987886/

McGrath, R., Cawthon, P.M., Clark, B.C. et al. Recommendations for Reducing Heterogeneity in Handgrip Strength Protocols. J Frailty Aging 11, 143–150 (2022). doi.org/10.14283/jfa.2…

Vigor to Frailty As a Continuum-A New Approach in the Study of Muscle, Mobility, and Aging Cohort pubmed.ncbi.nlm.nih.gov/37847228/ An updated operationalization of frailty.

Age is Associated with Dampened Circadian Patterns of Rest and Activity: The Study of Muscle, Mobility and Aging ( pubmed.ncbi.nlm.nih.gov/38416053/) Range of Acrotypes in SOMMA at baseline

The cellular bases of mobility from the Study of Muscle, Mobility and Aging (SOMMA) pubmed.ncbi.nlm.nih.gov/38429931/ Introducing a set of new findings from the SOMMA study in Aging Cell.

Lower muscle mitochondrial energetics is associated with greater phenotypic frailty in older women and men pubmed.ncbi.nlm.nih.gov/37987886/ New SOMMA paper linking mitofunction frailty

New paper from the Study of Muscle Mobility, and Aging (SOMMA). Childhood adverse life events and skeletal muscle mitochondrial function | Science Advances science.org/doi/10.1126/sc…

Childhood adverse life events and skeletal muscle mitochondrial function science.org/doi/10.1126/sc…

SOMMA's Skeletal Muscle Energetics data is featured at ICFSR 2004 (Friday March 22). Featuring Paul Coen Peggy Cawthon and Theresa Mau

#ICFSR24 has officially started with the Lifetime Achievement Award attributed to Dr. Anne Newman University of Pittsburgh and presented by Dr. Roger A. Fielding, PhD #frailty #sarcopenia

Great symposium at #ICFSR24 on Gene Expression Profiling from the SOMMA study AdventHealth CaliforniaPacificMed with Paul Coen, Greg Tranah and Russell Hepple #muscle #gene #research

Authors in this #JBMR Plus article investigate the association of urinary cadmium (U-Cd), as a surrogate for long–term Cd exposure, with bone and muscle health Jaymie Meliker Peggy Cawthon Eric Orwoll, MD Read more here: ow.ly/Pxwi50QLSfW