We are thrilled to share our latest work now published in Cell Reports! We combined #scRNAseq and #MERFISH on mouse models of type 2 skin inflammation to uncover a critical basophil-fibroblast crosstalk axis in amplifying inflammation. A thread 🧵 1/11

✨HUGE CONGRATULATIONS to Icahn School of Medicine at Mount Sinai's Dr. Cameron McAlpine Cameron McAlpine on being honored w/ the Dr. Harold & Golden Lamport Basic Research Award for demonstrating exceptional promise for making significant, long-term contributions to biomedical research!🎉👏

Fantastic HFpEF review from experts in the field out in JACC: Basic to Translational Science 🫀❤️‍🔥 jacc.org/doi/10.1016/j.…

New concept & changes to peer review to make it faster and more friendly: 👇 Unleashing the Power of the Beehive to Begin a New Era for JACC: Basic to Translational Science jacc.org/doi/10.1016/j.… This only works if you, our readers, authors and referees, embrace it!!

In this exploratory analysis, Tx w/ low-dose colchicine was assoc w/ an attenuated annual clonal growth in TET2 CH. Findings suggest potential for colchicine to curb proliferative advantage of key CH driver mutations jacc.org/doi/10.1016/j.… #ESCCongress #WCCardio #JACC Michael Honigberg, MD, MPP

Join Cameron McAlpine at #ESCCongress 2025 with #WCCardio for his presentation on "Damaged Hearts Require More Sleep" on Sunday, August 31. #CardioX European Society of Cardiology Icahn School of Medicine at Mount Sinai

Major congrats to Michael Honigberg, MD, MPP with THREE simultaneous senior-author publications during #ESCCongress25 each with a different first-author from his group! 👏 1️⃣ jacc.org/doi/10.1016/j.… JACC Journals 2️⃣ jacc.org/doi/10.1016/j.… JACC Journals 3️⃣ jamanetwork.com/journals/jamac… JAMA Cardiology

Discover more on heart-brain axis interactions in #CVD in our recent #CardiovascularResearch Spotlight Issue on the brain, heart, and vessels crosstalk composed by Guest Editors Daniela Carnevale, Costantino Iadecola & Joanna Wardlaw academic.oup.com/cardiovascres/… #ESCCongress

It was a pleasure to present data from the lab at #ESCCongress! There has been a great focus on neuronal and immune contributions to CVD.

Resistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia | Science science.org/doi/10.1126/sc…

nature.com/articles/s4158…

Proud to help launch NY-CURES advocating for sustained investment in NY science. Investing in NY science helps discover new cures, create jobs, and build a healthier future. I encourage everyone to learn more and join us: nycures.org

Connecting, sharing feedback, and finding collaborators are at the heart of Cell Symposia poster sessions—especially in the beautiful, historic setting of the New York Academy of Medicine. #CSNeuroimmune25 Immunity Neuron

Why do we sleep? And how? The 2 theories, broken down cell.com/neuron/fulltex… Neuron

PSA: Stop calling macrophages in tissue M1 or M2. These are not states that exist in biology. The only use of M1 is a macrophage cultured ex vivo with LPS and IFNg; and for M2: IL-4/13/10. Macrophages in tissues are highly complex and diverse and do not resemble either of the

It was an amazing day of systems cardiovascular science!

For anyone who has wanted a clear, authoritative summary of inflammation and cardiovascular disease, and where the science is heading, here it is. The 2025 ACC Scientific Statement on Inflammation and Cardiovascular Disease. JACC Journals jacc.org/doi/10.1016/j.…

It was a pleasure to speak at the ITMAT symposium at U Penn, a truly translational and multidisciplinary meeting!

Perspective discussing two recent Nature papers on the danger of yo-yo metabolism 👇 Metabolic Memory Resides in the Hematopoietic Marrow and in Arterial Resident Leukocytes | JACC: Basic to Translational Science jacc.org/doi/10.1016/j.…

JACC: BTS call for cardio-immunology 📣 ❤️‍🔥 jacc.org/call-for-paper… ❤️‍🔥 immune cells in CVD ❤️‍🔥 Immune-stromal cell interactions ❤️‍🔥 how do cardiovascular risk factors, including metabolism, influence the immune system? ❤️‍🔥 immune system in cardiovascular development and regeneration