#fluorescencefriday with centriolar rosettes in fixed RPE-1 cells, imaged confocal / with #3DSTED and #FLEXPOSURE adaptive illumination. Labeling: CP110🟥(STAR RED), SAS-6🟦(STAR ORANGE). Sample courtesy: Catherine Sullenberger & Jadranka Loncarek, Cancer Innovation Laboratory,

The MOSAIC reconfigurable microscope by Eric Betzig et al is finally out! MOSAIC integrates multiple advanced imaging techniques including light-sheet, label-free, super-resolution, and multi-photon, all equipped with adaptive optics: biorxiv.org/content/10.110…

Finally here! Our preprint on the MOSAIC, a multimodal adaptive optical microscope enabling non‑invasive in‑vivo imaging from molecules to organisms, is out. biorxiv.org/content/10.110… Eric Betzig Legant lab

Fantastic work (as always) from Che-Hang Yu and colleagues in Spencer Smith's lab Spencer LaVere Smith. Neat method to increase scan speed and/or FOV in 2p microscopy. Commercially available from Pacific Optica . I'd love to build this for a client at some point! biorxiv.org/content/10.110…

3D reconstruction of a 3-day-old zebrafish heart beating. Credit to Dr. Michael Weber (OpenSPIM). For those interested, you can read more about the acquisition and post-processing here: nature.com/articles/nmeth… #ZebrafishZunday

Ring deconvolution microscopy: exploiting symmetry for efficient spatially varying aberration correction Amit Kohli et al. doi.org/10.1038/s41592…

Achieving super-resolution microscopy for deep tissue imaging by cost-effective adaptation of two-photon laser-scanning microscopes 📹 Patrick Byers et al Multiphoton Imaging Lab, Munich University of Applied Sciences in Nature Communications ➡️ bpod.org.uk/archive/2025/7…

🔬Background Remover (BGR) is a novel software tool developed as a plugin to the well-known ImageJ program and designed to address the challenges of analysing fluorescent microscopy images characterised by low signal-to-noise ratios and heterogeneous backgrounds.

Fast, Bright and Reversible Rhodamine Tags for Live-Cell Imaging Julian Kompa et al. doi.org/10.1101/2025.0…

Look what THIS thing does.. It’s called your thymus, and it produces immunological peptides like thymosin alpha 1, which is anti-inflammatory, antiviral, and immunomodulatory Normally, you’d have to pay for that but this thing does it for free The catch? Chronic stress causes

3D-imaging of the mouse skull reveals the effects of ageing on the architecture of nerves & vessels 📷 Allison Horenberg et al Warren Grayson Johns Hopkins BME in Nature Portfolio Bone Research ➡️ bpod.org.uk/archive/2025/7…

PAPER OUT ✨ "hack" your microscope to work as a 3D printer! micrometer sized features at cm scale. <5$ in material costs per chip. from idea to experiment within a day. first paper of my phd in PertzLab PertzLab to make it through peer review! doi.org/10.1039/D5LC00…

HOW TO WEIGH A SINGLE E. COLI An E. coli cell weighs less than picogram. A grain of sand weighs about 60 million times more than that. A bacterium is so tiny that a few hundred thousand of them would fit comfortably on the head of a pin. But how do researchers know this? How

Scientists present an advanced new technique for live-imaging regenerating limbs, shown here on a sand flea. elifesciences.org/articles/10753…

3D-printed simulated tissue engineered to have the mechanical properties of living flesh & embedded fluid-filled capsules to mimic blood 📹 (sped up 2X orig) Adarsh Somayaji et al UMN Mechanical Engineering in Science Advances ➡️ bpod.org.uk/archive/2025/9…

Mario Ledesma-Terrón, Diego Pérez-Dones, David Míguez and colleagues present OSCAR, a framework to quantify 3D stacks with high cellular density. journals.biologists.com/jcs/article/13…

Anjali Kusumbe These are vessels in the dura mater!

🔬📱 Direct single-molecule detection and super-resolution imaging with a low-cost portable smartphone-based microscope. Our latest work published in Nature Communications. nature.com/articles/s4146…

"The Dance of the Coordinated Steppers" - the multi-dimensional Bresenham algorithm in action with non-linear acceleration. For more see my Patreon article: patreon.com/posts/cnc-su07… Open-Source Microscopy Microscopy Society BioImagingUK RMS #STEM FreeCAD (CAD+CAM+FEA)

A computer model comparing blood cell transport in healthy & cancerous tissue - includes physiologically significant parameters hard to measure in life 📹 Abhay Mohan & Prosenjit Bagchi, Rutgers University in Biophysical Journal ➡️ bod.org.uk/archive/2025/1…