Bryce Comstock (@bryce_comstock) 's Twitter Profile
Bryce Comstock

@bryce_comstock

MCASOM 25, Moffitt Radonc Incoming Resident, Father, Husband, Aspiring Radiation Oncologist. Tweets/Retweets are personal opinion, not that of my employer

ID: 56934461

calendar_today15-07-2009 05:20:42

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Piet Ost (@piet_ost) 's Twitter Profile Photo

📊 Breaking! FLAME trial 10-yr results show focal boost to MRI-visible tumors significantly improves outcomes in intermediate/high-risk prostate cancer: • bDFS: 86% vs 71% (HR 0.40, p<0.0001) • DFS: 81% vs 66% (p<0.001) #ESTRO25 ESTRO

📊 Breaking! FLAME trial 10-yr results show focal boost to MRI-visible tumors significantly improves outcomes in intermediate/high-risk prostate cancer:

• bDFS: 86% vs 71% (HR 0.40, p&lt;0.0001) • DFS: 81% vs 66% (p&lt;0.001)

#ESTRO25 <a href="/ESTRO_RT/">ESTRO</a>
Healio Gastroenterology (@healiogastro) 's Twitter Profile Photo

💉Three IL-23p19 inhibitors are set to shake up the #IBD market, challenging J&J Innovative Medicine’s #Stelara and its wave of #biosimilars “The choice of IL-23 agent hinges on accessibility, not just access...” — Dr. Stephen B. Hanauer, MD of Northwestern Medicine Game on 💥 bit.ly/4dls9vK

Shankar Siva (@_shankarsiva) 's Twitter Profile Photo

📢This might just be THE DEFINITIVE meta-analysis of PSMA PET for #prostatecancer recurrence. 🚨Meta-analysis of 43 studies (n=8,119) ⬆️Sensitivity from 48% at PSA 0.2–0.5 ng/ml to >90% at PSA >2. Congrats Declan Murphy marlon perera + team European Association of Urology (EAU)! ➡️link shorturl.at/unfn5

📢This might just be THE DEFINITIVE meta-analysis of PSMA PET for #prostatecancer recurrence. 
🚨Meta-analysis of 43 studies (n=8,119)
⬆️Sensitivity from 48% at PSA 0.2–0.5 ng/ml to &gt;90% at PSA &gt;2. Congrats <a href="/declangmurphy/">Declan Murphy</a> <a href="/drMPerera/">marlon perera</a> + team <a href="/Uroweb/">European Association of Urology (EAU)</a>! 
➡️link shorturl.at/unfn5
NRG Oncology (@nrgonc) 's Twitter Profile Photo

We couldn't think of a more important & timely discussion on #ClinicalTrialsDay. Our patient voices are what makes our research move the needle in #cancer care. Today, we share our discussion w/ patient advocate Tambre Leighn, MA, CPC she/her. New episode: nrgoncology.org/Podcast #CTD2025 ACRP - Assoc. of Clinical Research Profession

We couldn't think of a more important &amp; timely discussion on #ClinicalTrialsDay. Our patient voices are what makes our research move the needle in #cancer care. Today, we share our discussion w/ patient advocate <a href="/tambreleighn/">Tambre Leighn, MA, CPC she/her</a>. New episode: nrgoncology.org/Podcast #CTD2025 <a href="/ACRPDC/">ACRP - Assoc. of Clinical Research Profession</a>
Kevin Li (@kevndli) 's Twitter Profile Photo

Excited to share our latest work, now out in European Urology! We followed >166k prostate cancer survivors (1999–2019) using SEER-Medicare. RP+EBRT had the highest risk of urinary adverse events. EBRT surpassed RP at 10 yrs (with BT) & 14 yrs (alone). authors.elsevier.com/sd/article/S03…

Excited to share our latest work, now out in European Urology!

We followed &gt;166k prostate cancer survivors (1999–2019) using SEER-Medicare. RP+EBRT had the highest risk of urinary adverse events. EBRT surpassed RP at 10 yrs (with BT) &amp; 14 yrs (alone).

authors.elsevier.com/sd/article/S03…
Daniel E Spratt (@drspratticus) 's Twitter Profile Photo

X-torial: Cleaning up the misinformation about Joe Biden and #ProstateCancer that I am reading everywhere. The purpose of this is to provide education from someone who treats and studies PCa for a living, lead the USA National Comprehensive Cancer Network (NCCN) PCa guidelines, hold leadership in NRG Oncology National Cancer Institute

Keith Siau (@drkeithsiau) 's Twitter Profile Photo

Who would have thought - a low carb high fat (LCHF) diet is bad for cholesterol levels and cardiovascular disease 🤦🏻‍♂️

Stephen V Liu, MD (@stephenvliu) 's Twitter Profile Photo

More data against concurrent IO and XRT Journal of Clinical Oncology. Phase II study of concurrent pembrolizumab + chemoradiation for H&N SCC versus sequential CRT followed by pembro. Sequential had superior PFS and fewer immunosuppressive changes on serial biopsy. ascopubs.org/doi/10.1200/JC…

Moffitt Cancer Center (@moffittnews) 's Twitter Profile Photo

From #ASCO25: Amalia Stefanou, MD (Amalia Stefanou MD) shares how an APP-first care model boosted access for GI cancer patients and streamlined their path to treatment. #MoffittASCO25

Moffitt Cancer Center (@moffittnews) 's Twitter Profile Photo

Join Ben Creelan, MD, (Ben Creelan, MD) as he shares advances in immunotherapy for advanced non-small cell lung cancer being presented at #ASCO25! Read more: meetings.asco.org/2025-asco-annu… #MoffittASCO25 ASCO #NSCLC

Steven David (@drspdavid) 's Twitter Profile Photo

🔬 AVATAR trial published(ER+/HER2– MBC on AI + CDK4/6i): In OPD, SABR delayed therapy change (mPFS 9.9 mo) 🔷 44% on same Rx at 12 mo 🔷 36% at 24 mo Some received SABR 2–3× for new oligoprogressions—modified endpoints may better reflect its value. ascopubs.org/doi/10.1200/OA…

🔬 AVATAR trial published(ER+/HER2– MBC on AI + CDK4/6i): In OPD, SABR delayed therapy change (mPFS 9.9 mo)
🔷 44% on same Rx at 12 mo
🔷 36% at 24 mo
Some received SABR 2–3× for new oligoprogressions—modified endpoints may better reflect its value. ascopubs.org/doi/10.1200/OA…
Michael Hofman (@drmhofman) 's Twitter Profile Photo

#VIOLET Study of Terbium-161 (Tb-161) Beta/Auger therapy ASCO #ASCO25 First prospective trial of Terbium-161 in any tumour type 🟣 30 patient trial in prostate cancer. No dose limiting toxicities at highest level of radioactivity (7.4 GBq) 🟣 Very few side effects: 1 grade 3

#VIOLET Study of Terbium-161 (Tb-161) Beta/Auger therapy <a href="/ASCO/">ASCO</a> #ASCO25

First prospective trial of Terbium-161 in any tumour type
🟣 30 patient trial in prostate cancer. No dose limiting toxicities at highest level of radioactivity (7.4 GBq)
🟣 Very few side effects: 1 grade 3
Shankar Siva (@_shankarsiva) 's Twitter Profile Photo

Mayo Clinic - wow what teamwork! This place just oozes good culture! For a busy clinical facing-practice; so impressed with working environment. No wonder the staff love working here! Thanks for having me as visiting prof 🙏🏽🙏🏽

<a href="/MayoClinic/">Mayo Clinic</a> - wow what teamwork! This place just oozes good culture! For a busy clinical facing-practice; so impressed with working environment. No wonder the staff love working here! Thanks for having me as visiting prof 🙏🏽🙏🏽
American Gastroenterological Association (AGA) (@amergastroassn) 's Twitter Profile Photo

We are supportive of the Gerald E. Connolly Esophageal Cancer Awareness Act of 2025 and are pleased to hear the House passed it by voice vote. This bill references AGA screening guidelines in the findings and requires a GAO study of esophageal cancer costs.

American Gastroenterological Association (AGA) (@amergastroassn) 's Twitter Profile Photo

This is a step in the right direction. It marks the first time there has been legislation devoted to esophageal cancer and it will provide useful data.

Shankar Siva (@_shankarsiva) 's Twitter Profile Photo

Drew Moghanaki “possibility VALOR phIII RCT of surgery vs SABR will show no difference in stage I #lungcancer” #radonc #SABR2025 🇨🇦 🟰several studies showing no diff ⬇️ trends for surgery in 🇺🇸 🤔 sampling LNs in solid dom GGO not needed ⚖️ ?benefit of lobectomy nasser altorki

<a href="/DrewMoghanaki/">Drew Moghanaki</a> “possibility VALOR phIII RCT of surgery vs SABR will show no  difference in stage I #lungcancer” #radonc #SABR2025 🇨🇦
🟰several studies showing no diff
⬇️ trends for surgery in 🇺🇸
🤔 sampling LNs in solid dom GGO not needed 
⚖️ ?benefit of lobectomy <a href="/AltorkiNasser/">nasser altorki</a>
Daniel E Spratt (@drspratticus) 's Twitter Profile Photo

This is very important for patients to be aware of a completely non-invasive option for early stage lung cancer that in RCTs has at least similar outcomes to undergoing thoracic surgery. Hopefully National Comprehensive Cancer Network (NCCN) NSCLC panel can revisit this. Great for patients to have options and seek

Drew Moghanaki (@drewmoghanaki) 's Twitter Profile Photo

It’s time to remove the designation of “unresectable” or “inoperable” when considering the option of radiotherapy for people with lung cancer. nejm.org/doi/full/10.10…

It’s time to remove the designation of “unresectable” or “inoperable” when considering the option of radiotherapy for people with lung cancer. nejm.org/doi/full/10.10…