Took this photo a few days ago while biking home. It made me think about today, and how desperately we need somebody who will fight for, rather than antagonize, the little guys out there. I can’t vote, but if you can, PLEASE make it one more for Joe Biden #Election2020

In our newest publication Science Magazine, Iain Clark, Michael Wheeler and Cristina Gutiérrez-V developed RABID-seq, a novel method for tracing astrocyte interactions at the single-cell level, and highlight a pathway of astrocyte-microglia cross-talk in CNS inflammation. science.sciencemag.org/content/372/65…

Can't believe I get paid to do this.

So grateful to have been surrounded by amazing science and even better people for the past ~2 years. Missing it already!

Olympic Gold for Canada!!!! 🇨🇦 🥇 #CANWNT 🇨🇦1:1(3:2)🇸🇪 SWE #Tokyo2020 🥇 #RiseHigher

Excited to share our preprint “CRISPRi screens in human astrocytes elucidate regulators of distinct inflammatory reactive states” Led by Kampmann Lab Kun Leng, great collaboration with Ethan Lippmann Matthew Schrag Steve Fancy Erik Ullian Ye Zhang biorxiv.org/content/10.110…

Thrilled to have our preprint out! Lysosomes do really interesting things in inflammatory reactive astrocytes—check it out!

Explore our new #astrocyte CRISPR screens now on CRISPRbrain! As always, great to work with DataTecnica. Read more about the astrocyte results in these pre-prints by Kun Leng and Brendan Rooney: biorxiv.org/content/10.110… biorxiv.org/content/10.110…

Congrats to a phenomenal mentor and even better human being, Dr. Kun Leng!

Perfect weather for losing track of time and cups of coffee 🎄🇨🇦

Really looking forward to getting back into astrocyte land on Apr. 21!

Excited that we (Kun Leng, ⁦Brendan Rooney⁩) contributed to this work led by Marcus Chin (⁦Kao Lab⁩ ⁦Michelle Arkin⁩): Phenotypic Screening Using High-Content Imaging to Identify Lysosomal pH Modulators in a Neuronal Cell Model pubs.acs.org/doi/10.1021/ac…

Great to be home for a few days!

Excited that our work, led by Kun Leng, is out today in Nature Neuroscience today: CRISPRi screens in human iPSC-derived #astrocytes elucidate regulators of distinct inflammatory reactive states nature.com/articles/s4159…

Utilizing rare human brain biopsies we address: 1) Which cell types likely make amyloid? 2) How do microglia respond to amyloid and how does this compare to states in mouse models? 3) What neuronal states precede cell death in AD? Paper out today! cell.com/cell/fulltext/…

Many exciting updates to our preprint! Check it out 👇🏼

Thrilled to have our paper out! Much credit to Kun Leng and Martin Kampmann for advancing the story over the past few years. Beyond our findings, I hope the deposited data will help folks advance our understanding of the molecules and functions of this fascinating pathway