Thread on the reporting of hierarchical outcomes inspired by 1 of the only 2 #Impella RCTs.

Daniel Ambinder, MD Mamas A. Mamas MIЯVΛƬ #IC ༄ ｡° Dr Anastasia Mihailidou FAHA FCSANZ FESC Dr. Purvi Parwani Erin D. Michos, M.D. Musa A. Sharkawi Jay Mohan, D.O., FACC, FSCAI, FASE, RPVI John P Erwin III MD MBA MACC (#BigPoppy ) David H. Wiener, MD Sravya Chirumamilla, MD, FACC ♥️ Nadeen N. Faza, M.D. Evandro Martins F. MD Edinson Garcia. MD Dr Shariq Shamim Pushpa Shivaram MD FACC Amit Goyal MD MAS 😎#EchoFirst tissue doppler shows ⬆️medial E’ velocity in #constriction since lateral wall is tethered to the pericardium which is the reverse(annulus reversus)of normal where lateral 10-15 cm/s E’velocity is > medial 8-10 cm/s🆚CM both medial &lateral E’ velocity⬇️ h/t Jae K. Oh

Congrats Nicolas Santi for presenting our data and showing how arterial age is relevant for assessing disease activity and predicting future #TAA expansion. How the aorta ages is important for all of us, but particularly interesting among those with aortopathy. Dr Anastasia Mihailidou FAHA FCSANZ FESC

Bravo Dre Thais Coutinho, récipiendaire du prix 2019 d'excellence internationale de l'ICUO! Ce prix reconnaît l'impact & le leadership mondial de Dre Coutinho dans la recherche sur la santé cardiaque des femmes. Heureux que bébé Sofia reçoive le prix avec Dre Coutinho!

Attention❣️Are you a physician/cardiologist/EP in the #Ottawa region who believes in the power of #exercise? Refer your patients with #AFib to our study⬇️More info⬇️ Recruitment has been slow〽️any tips from the #AcademicTwitter #cardiotwitter community? RT Academic Chatter™

How social distancing works, in animation form: uOttawa | Faculté de médecine, Faculty of Medicine School of Epidemiology and Public Health Brainheartnexus Amy Johnston Erin D. Michos, M.D. Dr. Purvi Parwani Mamas A. Mamas Dr. Martha Gulati ♥️🫀❤️‍🩹🇨🇦 Ritu Thamman MD Shelley Zieroth Harriette Van Spall, MD MPH 🇨🇦 Robert (quint vaxxed) Chen Andrew Crean Rob Beanlands

Disappointing news for Docycycline in AAA - there was a potential effect on matrix remodeling in theory, but did not pan out clinically or at the molecular level. Maral Ouzounian Jennifer Chung Josh Beckman Mohammad A. Zafar, MD Ismail El-Hamamsy, MD, PhD

*Constrictive Pericarditis Tweetorial* A 50-year-old male with a prior cardiac surgery with right heart failure. Exam shows a JVP of 15 cm and an estimated 20 kg of interstitial edema. What's abnormal? What are we looking for? #echofirst #FOAMed 1/

Research by Kevin Boczar and Thais Coutinho shows that measures of aortic stiffness and pulsatile arterial load are associated with future #TAA expansion. These may help improve assessment of disease activity and refine risk stratification in patients. ow.ly/JMYC30roFaD

#JournalNC: Does #statin have an effect on inflammatory #ThinkPET FDG uptake in the thoracic #aorta, #spleen & bone marrow 🦴 in pts with #HIV? Read here👉bit.ly/3IjJCF3 #CVNuc ASNC Society

Recently published ⁦⁦⁦Journal of Nuclear Cardiology⁩ , UOHI researchers found HIV+ pts had markers of systemic inflammation. Tx with low-dose rosuvastatin in the HIV+ group ⬇️bone marrow, spleen & thoracic aortic FDG-uptake when rescanned with PET/CT imaging pubmed.ncbi.nlm.nih.gov/34820771/

#CTD2022 #TalkClinicalTrials Kevin Boczar Rob deKemp Rob Beanlands

In a study published Hypertension, Heart Institute investigators' findings demonstrated a potential role for noninvasive hemodynamic assessment to better predict disease activity & refine risk stratification in patients with Thoracic Aortic Aneurysm #CTD2022 bit.ly/3lkS4JH

#HotOffThePress Ccanakinumab is not cost effective from Canadian healthcare system perspective #CJCOpen 👉 cjcopen.ca/article/S2589-… Kevin Boczar Rob Beanlands

A MUST READ: #JACCIMG expert panel statement on best practices for #cvImaging device-related infections & #endocarditis. bit.ly/39Q5cUO #echofirst #whyCMR #YesCCT #CardioTwitter

Great work by Kevin Boczar Heart Institute UOHI Research Services CJC Journals #Cardiology #CardioTwitter #CardioEd

Check out our article describing the role of inflammation in atherosclerotic❤️‍🔥disease!!! 🔥🔥🔥 Rob Beanlands #CardioEd #Cardiology #CardioTwitter Hearts on fire: the role of inflammation in the pathogenesis of atherosclerotic cardiovascular disease pubmed.ncbi.nlm.nih.gov/35640808/

1/2⭐️⭐️E-pub alert! After establishing the utility of measured #aorticstiffness in predicting future #TAA growth, Kevin Boczar and our team assessed whether mathematically estimated aortic PWV (no need for equipment) could do the same. The answer? YES! bit.ly/3Q5xNpi

Check out our latest research (with Rob Beanlands ). FDG PET evidence of vascular inflammation 🔥 after CAP 🫁 From @jaccjournals jacc.org/doi/10.1016/j.…