Our latest longitudinal study on trends in #benzodiazepines and #Z-drug prescribing in Hong Kong has just been published with Elsevier in The Lancet Reg Health-West Pacific. We found increasing trends from 2014 to 2023, with a notable increase in young adults. Esther Chan @ CSMPR HKU

For elderly Asia patients with acute myeloid leukaemia, venetoclax combination with hypomethylating agents showed superior overall survival and less transfusion needs than hypomethylating agents alone, especially the >=75 years group. CSMPR_HKU journals.sagepub.com/doi/10.1177/20…

Our multinational network cohort study shows that extensive multi-organ involvement of post-COVID-19 condition over the short-term period and the subside in risk for most complications over the medium- and long-term. journals.sagepub.com/doi/10.1177/01…

🔬Recent #multinational study involving 22.4M individuals from 🇺🇸🇬🇧🇫🇷🇮🇹🇩🇪 showed extensive multi-organ involvement of post-COVID-19 condition over the short-term and the subside in risk for most complications over time📊 journals.sagepub.com/doi/10.1177/01… #COVID19 #LongCovid #PublicHealth

Our 10-Year Retrospective Cohort Studies in UK and HK finds that younger age of #hypertension onset is associated with higher risks for #cardiovascular events and #mortality. Paper published on Journal of Primary Care & Community Health Sage Journals. journals.sagepub.com/doi/10.1177/21…

The #validated #Cantonese-Chinese #translation of the Pharmacy Services #Questionnaire #PSQ is a reliable #instrument to assess services #satisfaction by community pharmacies. See full article published in J PharmPolicy & Prac tandfonline.com/doi/full/10.10…

My lab’s latest The Lancet Psychiatry study showing increased infections following clozapine use; excellent work by my student Yuqi Hu and the rest of my team, with special thanks to psychiatry, family medicine, & pharmacy colleagues & collaborators 🥂 thelancet.com/journals/lanps…

Our #EJPC paper found that the Risk Assessment and Management Programme for #Hypertension (RAMP-HT) supplementing usual care associated with reduced relative risk of #CVD and all-cause #mortality in HT patients compared to those receiving usual care only. academic.oup.com/eurjpc/article…

My lab's latest study shows that post-COVID multimorbidity incidence in people with 1 pre-existing condition is up 26% with a rate diff. of ~2/100 PYs - but prior vaccination offsets this risk increase substantially! Available in Journal of Infection now! sciencedirect.com/science/articl…

"Emulating Six Cardiovascular Outcome Trials of Antidiabetic Drugs in Individuals with Type 2 Diabetes: Analyses Based on Real‐World Databases from Korea and Taiwan", has been published by our international team! Read ascpt.onlinelibrary.wiley.com/doi/10.1002/cp…

Duramax, a reinforcement learning framework designed to optimize long-term lipid-modifying therapy for CVD prevention. It helps bridge the gap between AI-driven precision and real-world clinical utility. nature.com/articles/s4174…

Our paper found #specialist outpatient clinic (#SOPC) service disruption like #COVID was associated with increased risk of #mortality and #CVD among #DM patients. Findings support #primarycare clinics are essential in public health crises. …ubs.pericles-prod.literatumonline.com/doi/10.1111/do…

Read our paper on 18 Countries and HK Opioid Prescribing Trend from 2001 to 2019. Very big differences between countries and US is going down. link.springer.com/10.1007/s40263…

Our JACC Journals paper found that #statin use for primary #prevention was associated in all-cause #mortality and major #CVD reductions with a very low risk of adverse effects among #T1DM adults, guiding personalized statin #treatment decisions in T1DM. sciencedirect.com/science/articl…

Article link: doi.org/10.1016/j.jacc… Accompanying editorial: doi.org/10.1016/j.jacc…

Our World Psychiatry (IF=65.8) World Psychiatric Association (WPA) wpanet.org Letter on a new cohort study led by Wenxin TIAN and myself CSMPR_HKU HKU Pharmacy HKU Medicine The University of Hong Kong showing a rare elevated risk of gynecologic cancers after prolactin-increasing antipsychotic use 🥂 onlinelibrary.wiley.com/doi/10.1002/wp…

Our simulation model supports the cost-effectiveness of PSA screening in China. Personalised screening based on genetic risk may provide an efficient alternative to uniform strategies by reducing unnecessary interventions for lower risk individual.sciencedirect.com/science/articl…

Our age-specific models accurately predicted the post-acute #mortality risk within 1 year of #COVID infection, optimizing clinical strategies and resource allocation in global burden of #LongCOVID management. Published on QJM. academic.oup.com/qjmed/article/…

Our CMAJ study found a less stringent #risk threshold of 30% for intensifying #PrimaryCare encounters frequency is associated with increased overall #CVD risks and all-cause #mortality of aged 60+ #T2DM patients, but not for those below 60. cmaj.ca/content/197/32…

Excited to share our latest study in The Lancet: long-acting injectable antipsychotics (LAIAs) are more effective than oral and equally safe for older people, except for higher risk of EPS with typical LAIAs, but not with atypical LAIAs. Esther Chan @ CSMPR HKU thelancet.com/journals/lanps…