Important reading from Dale Needham, MD, PhD, Mona Hopkins and others With the significant numbers of middle aged patients being discharged post #COVID19 from ICU these data are essential reading #COVID19 #thisgenerationspolio thorax.bmj.com/content/75/1/17

In a stepped-wedge, cluster RCT incl 10 centres and 1749 ICU patients, a multicomponent nursing intervention program on delirium had no effect in preventing or treating delirium. 6 min of additional prevention is not much @markvdboogaard : what happened? atsjournals.org/doi/10.1164/rc…

Our latest publication, now out! DEVISE - Delirium Variability is Influenced by the Sound Environment. Daniel Fabbri @AyushSangari Elizabeth Emhardt @theology_med VUMC Anesthesiology @VUMC_Insights Vanderbilt Health Jesse Ehrenfeld MD MPH SCCM Ruth Kleinpell Springer Nature Steve Keller rdcu.be/cnehf

Random thought: What if the NIH allowed an option for submitting a traditional Specific Aims page..or, as an alternative, a full-page "Specific Aims Infographic"? How would things change with grant applications?

"Suffering in silence" -- survey-based study on the important and underrecognized issue of mental health impairments in medical school applicants. Asking your premedical students a simple "how are you doing?" may go a long way .... tmblr.co/ZEKAexasEn6dqW…

Multi-intervention protocol to improve sleep quality in a coronary care unit academic.oup.com/eurjcn/advance…

Ambition without knowledge .. is like a boat on dry land.

I was hopeful that melatonin would work, but this large & robust MC-RCT is pretty convincing that 4 mg qhs doesn't help sleep or delirium. so I think it's time to recommend against using melatonin in Internet Book of Critical Care 📖 😢 any disagreement? article: link.springer.com/epdf/10.1007/s…

Very grateful for the membership of Biren Kamdar in all the teaching, mentorship, and guidance to get to this publication! Started this when I was a bb medical student 🤗 👇🏽 Circadian rhythmicity (or lack thereof) in ICU patients! onlinelibrary.wiley.com/doi/10.1111/js…

using a benzodiazepine to treat delirium-induced agitation x.com/ohshidt/status…

Sleep hygiene is part of our occupational therapy role. Looking at night time routines, discussing strategies & identifying areas to develop. Suggesting writing down thoughts & having a notebook by the side of the bed to support emotional wellbeing & planning for the next day💤🛏

Pets in the ICU should become a common healing presence. It is doable and right (given certain considerations & controls of course). His #dog might do more to #heal him than I ever will. Just sayin’ H/T Professor Katarzyna Kotfis, MD, PhD, EDAIC x.com/weselymd/statu…

Vitamin D supplementation did not prevent fractures among relatively healthy middle-aged and older adults in the landmark VITAL trial. jwat.ch/3cHHMCp #VitaminD #fracture

🚨 Vasopressors commonly used in ICU, ER, & OR #MedEd #MedTwitter #FOAMcc ♥️ these must see graphics from Journal of Brown Hospital Medicine

Volatile anesthetics for #ICU sedation ➡️ ventilators adaptable to deliver ➡️ effective even in #ARDS ➡️ rapid on/offset, no accumulation ➡️ analgesic effect: opioid-sparing? ➡️ may preserve spont breathing ➡️ immunomodulatory/organ-protective effects? 🖇️ rdcu.be/cUVYk

Development and Evaluation of an Intensive Care Unit Video Series to Educate Staff on Delirium Detection | ATS Scholar atsjournals.org/doi/full/10.34…

hot take on the AID-ICU trial of haloperidol for management of delirium in ICU 🔥 this is the largest MC-RCT to date on haloperidol for treatment of delirium (in comparison, MINDS enrolled 192 patients in the haloperidol group). nejm.org/doi/full/10.10…

1/🧵 Haldol for ICU patients⁉️ 📌 Not so fast 📌 Study of N=1000 backs-up our MIND-USA study - full 🧵👇 📌 Haldol doesn’t treat #delirium 📌 Calms pts & can ⬇️ danger 📌 Delirium care is about non-pharm approaches - the Dr. DRE… bit.ly/3sz27Pe

Thrilled to see our Research Statement on ICU Sleep and Circadian Disruption published. Did this with an amazing, wise group of scientists.  doi.org/10.1164/rccm.2… #ATS Xavier Drouot Mojdeh Heavner Brian Anderson Makayla Cordoza, PhD, RN @devlinpharmd Rosalind Elliott Brian Gehlbach ☕️ 🩺 🎹