🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Check out some exciting new work from Scott McCain here!

Elizabeth Villa (Elizabeth Villa, UCSD BioSciences), and colleagues, have unveiled the structure of the nuclear basket, key to how cells control what enters/exits the nucleus. This could reshape our understanding of gene expression & DNA organization. More: cell.com/cell/pdf/S0092…

Humbled and honored to be selected as a Damon Runyon fellow!

We’re looking for a PhD student to join the team - interested in timing + robustness of development and hoping to gain computational and/or experimental chops? Reach out to me or our students to learn about a PhD at a premier research institute in Europe: dorrity-lab.com

Less than 1 week left to apply for #SMB2025 ! Info on the flyer. 🔬⛷️👩‍🔬🏂

Without foundational knowledge of human biology and disease made possible through basic research, solutions to real-world health problems through applied research would not be possible. My colleagues & I describe the importance of #NIH-supported basic research and how it advances

Hey procrastinators- I’m looking at you! Today is the LAST day to submit your abstract for #SSP2024 and secure early registration pricing! If I weren’t organizing, I’d probably be registering today 😅- so you can too! See you in Cam in Oct! ssp2024.org

My first postdoc paper is now in J. Am. Chem. Soc.! By incorporating SuFEx chemistry and protein engineering we covalently stabilized an 18-subunit protein-peptide complex, enhancing stability and homogeneity for high-precision applications like DNA sequencing. 1/9 pubs.acs.org/doi/10.1021/ja…

High-throughput discovery of inhibitory protein fragments with AlphaFold Massachusetts Institute of Technology (MIT) 1/ This study introduces FragFold, a novel computational method that leverages AlphaFold for high-throughput predictions of protein fragment binding, enabling the discovery of inhibitory fragments

Check out Li lab postdoc Andrew Savinov's (Andrew Savinov) updated manuscript on our computational approach to predict inhibitory protein fragments at scale -- now complemented by extensive new deep mutational scanning experiments. MIT Biology MIT Science @HHMINews

So excited to announce that the Kappel Lab will open at UCLA UCLA Chem & Biochem in July 2025! We’ll combine high-throughput experiments and computation to build predictive sequence-structure-function models of RNA, proteins, and their interactions. More here: sites.google.com/view/kappellab/

Ever wonder how cells survive under starvation? During my postdoc in the Joey Davis @[email protected] , I designed a novel SILAC pulse labeling-qMS workflow to track proteome degradation under mTOR inhibition. Preprint here: doi.org/10.1101/2024.0… Curious about how cells adapt? Keep reading!