Complementing metabolomics to track reactive intermediates, e.g. CoA-esters: Stable Isotope Labeling of Reactive Electrophiles (SILORE) reveals new C. elegans biochemistry, out now Laura Kiessling: pubs.acs.org/doi/10.1021/ac…

Interested in protein-metabolite interactions? We highlight some experimental approaches here w/ @bti_skirycz sciencedirect.com/science/articl…

Humble worm farmer with modern mass spec feeling excited about our work published in nature! Great collaboration between Erik Andersen Schroeder Research Group and @WalhoutMarian. “Every molecule has a history.” nature.com/articles/s4158…

BREAKING NEWS: The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”

New pathways for serotonin biosynthesis and metabolism in C. elegans, with Jingfang Yu and bennett_fox out at Nature Chemical Biology: nature.com/articles/s4158…. Thanks to Merly Vogt and Oliver Hobert for a great collaboration; Ji Sze’s insightful commentary at nature.com/articles/s4158…

Very excited to share our recent work, which is posted on the BioRxiv today, "NLRP3 Cys126 palmitoylation by ZDHHC7 Promotes Inflammasome Activation". doi.org/10.1101/2023.1… Thank Dr. Lin for the overall guidance! Thank all the authors for their kind help!

Sirtuins interact with spermidine metabolism - check out Bingsen's paper, out in Nature Chemical Biology nature.com/articles/s4158…… today! Also see our press release "New Insights into Metabolites That Control Aging and Disease"

A nice summary and comments on our acylspermidine story ‘The buck stops with spermidine | Nature Chemical Biology’ nature.com/articles/s4158…

Fact: The nematode C. elegans predominantly uses a 17-carbon, branched chain fatty acid for protein cysteine fatty acylation (commonly called 'palmitoylation' in mammals)

Tiny worm, giant leap: Discovery of highly specific fatty acid attachment to proteins Boyce Thompson Inst PNASNews doi.org/gtfj2c phys.org/news/2024-01-t…

Congratulations 2024 Am Soc for Mass Spec Award Recipients! We look forward to celebrating you all at #ASMS2024 in Anaheim. Full announcement: asms.org/about-asms-awa…

My review article on metabolite derived protein modifications with ⁦Schroeder Research Group⁩ is now online! nature.com/articles/s4158…

Bingsen's perspective on how metabolic state feeds back on protein function and physiology: "Mechanisms of metabolism-coupled protein modifications" at Nature Chemical Biology: nature.com/articles/s4158…

A new Perspective by Bingsen Zhang and Frank Schroeder details the intricate coupling between metabolism and post-translational modifications nature.com/articles/s4158…

Congratulations to Tae, Arif, and Chris on publication of their Nature paper, reporting a new class of bile acids that regulate cholesterol metabolism: nature.com/articles/s4158…

Nature research paper: Host metabolism balances microbial regulation of bile acid signalling nature.com/articles/s4158…

Beneficial gut microbes and the body work together to fine-tune fat metabolism and cholesterol levels, according to a new preclinical study out of Weill Cornell Medicine and Boyce Thompson Inst. nature news.cornell.edu/stories/2025/0…