The C3FIT trial was a protocol-driven multicenter cluster-randomized trial. Here is Seemant Chaturvedi’s perspective on the results at #ISC25

As Dr Nerissa Ko mentioned, a stroke patient survivor reminded us why we do what we do. Dr William Mack with a grateful stroke patient who recovered speech after a healed carotid dissection. #ISC25

Dr Turc presenting at #ISC25 on thrombolytics in pts on DOACS, which in my understanding is more commonly than the states. 🧪Per ESOC guidelines, don't use PTT, but use Xa <0.5u/ml or TT for dabiga. 🏥This is supported by observational data.

BEST trial: In a Phase 2 trial, BXOS110, a novel PSD-95 protein inhibitor administered within 3 hours after stroke onset demonstrated potential for improvement in functional outcomes (mRS 0-2 at 90 days) after stroke, paving the way for Phase 3 study in the future. #ISC25 #aha

HOPE Results Presented at #ISC25

Very proud of this guy ... CONGRATULATIONS Cyprien Rivier ! ! ! For receiving the Vascular Cognitive Impairment Award @ #ISC25 for the abstract "Integrated Genomic/Proteomic Profiling Supports Cathepsin-B as a Drug Target in CSVD” isc.hub.heart.org/daily-coverage… Yale Neurology

It was a great experience presenting our findings from the CEDAR study at #ISC25. #TakeMeBacktoLA

#ISC25 although the science is exciting, the best part of International Stroke Conference always is seeing the UAB fam again! 😁

One cannot have asked for a better Chair than LaurenHSansing! Me and the entire program committee have loved her leadership and how much she cares! Excited for #ISC2026 at New Orleans! AHA Science

Mostly co-pilot! Tagging the Schwamminator! Dr. Lee Schwamm LaurenHSansing

Genetic determinants of insufficiency of the collateral circulation journals.sagepub.com/doi/full/10.11…

Neuroprotection is effective when administered in a specific time interval (it can prevent only infarct growth between administration and recanalization). Kudos to Mayank Goyal Johanna Ospel, MD PhD Michael D Hill Bijoy K Menon thelancet.com/journals/laneu…

Thrilled to welcome this incredible crew of neurology residents to our family. Welcome to Calgary!! DCNS Calgary UCalgaryMedicine

Congratulations to Dr. Lawrence Korngut on receiving the King Charles III Coronation Medal from ALS Canada for his research contributions.

ISC2026 is at New Orleans! Enjoy the best stroke science at the best city in the world for food! timeout.com/travel/worlds-… AHA Science Stroke AHA/ASA LaurenHSansing Thanh Nguyen 🇺🇦 Dr. Lee Schwamm Seemant Chaturvedi

🚨In this prespecified analysis of the AcT RCT, we examined safety & efficacy outcomes of thrombolysis with tenecteplase & alteplase in elderly patients. 23% mRS 0-1 among >=80y vs 43% <80y. No difference in sICH. ahajournals.org/doi/10.1161/ST… nishita singh DCNS Calgary Bijoy K Menon

Last date for ISC session submissions is tomorrow!!! This is your chance to shape ISC2026! Stroke AHA/ASA LaurenHSansing Thanh Nguyen 🇺🇦 Seemant Chaturvedi AHA Science

Calling all stroke researchers and clinicians!! Deadline for invited symposia suggestions for #ISC26 in New Orleans is Thursday, April 3, 2025 at 6:00 a.m. ET! New categories!! Get your ideas into the conference :) AHA Science Bijoy K Menon Shadi Yaghi Dr. Lee Schwamm

🚨In focus groups for ACT-GLOBAL, our ongoing stroke adaptive platform trial, patients & caregivers supported APT design but identified priorities re: execution to safeguard patient autonomy & safety doi.org/10.1159/000546… Bijoy K Menon Karger Publishers DCNS Calgary The George Institute for Global Health

The Symptomatic Carotid Outcomes Registry (SCORE) has now enrolled 2/3 of the target patient number. Planning to complete enrollment by the end of 2025. Let's keep the momentum going! Look for the poster at #ESOC2025 Thanh Nguyen 🇺🇦 Luciano Sposato 🇦🇷🇨🇦 Bijoy K Menon European Stroke Org American Academy of Neurology