Harvard chemist and molecular biologist David Liu invented gene editing tools that can correct and rewrite defective genes. His research could one day help hundreds of millions of people with genetic diseases, including sickle cell and muscular dystrophy. cbsn.ws/4oyLApL

New preprint! We identified Vipr2-expressing BNST neurons as a distinct population of the oval nucleus that promotes feeding, is activated by food restriction, is non-overlapping with appetite-suppressing PKC delta neurons, and projects to hypothalamus. biorxiv.org/content/10.110…

🤯Wow really interesting work!!! Congratulations Ardem Patapoutian and coauthors!! PIEZO channels link mechanical forces to uterine contractions in parturition | Science science.org/doi/10.1126/sc…

The #NestlerLab is VERY EXCITED to join our colleagues from @icahnmountsinai, the #FriedmanBrainInstitute & #NashNeuroscience at #SfN2025! In #SANDIEGO? Make sure to stop by, check out our presentations and learn about our work. See Our Itinerary Here👉files.constantcontact.com/d41ee115401/ec…

Using a single prime editor to rescue premature stop codons across many different diseases: a clever and promising way to dramatically scale prime editing therapies.

Our paper is out in nature! Oncogenes are often copy-number amplified on extrachromosomal DNA (ecDNA) in cancer, but how is ecDNA inherited by dividing cells? Here we identified elements within ecDNA that promote its retention in dividing cells. 1/11 nature.com/articles/s4158…

Epigenetic editing: from concept to clinic nature.com/articles/s4157…

Remarkable story of high school team who used CRISPR to make a rapid diagnostic test strip for Lyme disease, speeding dx from 2 weeks to days

Improved spike-in normalization clarifies the relationship between active histone modifications and transcription biorxiv.org/content/10.110…

Is anyone else planning on going to this? March 2026 in Geneva! keystonesymposia.org/conferences/co…

🎉CONGRATULATIONS to the #MazeLab's Benjamin Weekley, PhD who has received an NIH F32 this year from National Institute of Mental Health (NIMH) to study "Mechanisms of Histone Serotonylation and MLL5 in Coordinating the #Epigenome during #Neurodevelopment". Learn More about Dr. Weekley's work👉reporter.nih.gov/search/IzFGOTR…

Epigenetics Update - Widespread association of Polycomb complex–deposited histone H2A monoubiquitylation with enhancers and neuronal gene regulation bit.ly/4rw5p2I #Epigenetics #Polycomb --- Gain deeper insights into gene regulation; epigenometech.com

New work from Nikolaos Chatziris describes a method for genetically tagging neurons that respond two different stimuli. biorxiv.org/content/10.648…

FIRST PREPRINT FROM MY POSTDOC: curious about dopamine receptor expressing cells in regions beyond the striatum? Read below about D1 and D2 cells in the ventral hippocampus & how they differentially affect motivated behavior and memory expression! assets-eu.researchsquare.com/files/rs-80797…

The discovery of sugars, including ribose and glucose, in samples from asteroids returned by spacecraft, means “material with all three components necessary to life could have been dispersed to prebiotic Earth and other inner planets” (nucleobases and amino acids were previously

These are 10 essential science reads from the past year go.nature.com/4pOVCD8

DON'T MISS this FASCINATING LECTURE! On Friday, December 12th, 3pm, Join #MSNseminars and hosts Drs. Giada Dirupo, Dina Vázquez Carrillo and Freida A Blostein when Rockefeller University's Dr. Lucas Y. Tian presents “Neural basis of symbol compositionality".

New preprint from Mari Anguiano Maribel Anguiano & Run Zhang! tinyurl.com/muzs33je Mari used a membrane-TurboID (engineered by Run) to find local proteomes in vivo at distinct mPFC axons & synaptic protein changes during cocaine. Happy to share protocols/reagents!