The ADS would like to invite you to join the second series of the Australian Islet Biology Lunchtime Seminar via Zoom. Join Dr Belinda Yau and Dr Balasubramanian Krishna Murthy this coming Thursday, 30 April at 1:00pm AEST. Link: uni-sydney.zoom.us/j/97927134074 University of Sydney SVIResearch

New preprint from our lab: the absence of VPS41 leads to #diabetes in mice due to insulin secretion defects. A big thank you to our collaborators,KebedeLab at Charles Perkins Centre in Sydney,Judith Klumperman in Utrecht and @JFitzpatrickWU WashU Center for Cellular Imaging in St Louis! tinyurl.com/y8da5mzh

The next #AIBLSS will feature our 1st international speaker of the series Professor Jim Johnson from University of British Columbia, Canada. Please join us on uni-sydney.zoom.us/j/97927134074 on Thursday 7th of May at 1:00PM Australian Eastern Standard Time.

Paper in Press: "A fluorescent timer reporter enables sorting of insulin secretory granules by age" – #CellBiology #MolecularBasesinDisease jbc.org/content/early/… University of Sydney The University of Chicago Garvan Institute of Medical Research

Journal of Biological Chemistry University of Sydney The University of Chicago Garvan Institute of Medical Research Very excited to see our paper in Press Journal of Biological Chemistry. Congratulations Belinda Yau and thank you to all our collaborators and the NHMRC for funding the project.

Totally consistent with our observation in mice islets - newly synthesized insulin are preferentially secreted in glucose clamping situations. Congratulations!

Thank you Jim Johnson, PhD for an outstanding seminar. Congratulation Søs Skovsø, PhD for the wonderful data Jim presented. Thank you all for joining us. For those who couldn’t, we will share the link to the recording very shortly. See you all next week for more amazing Islet Biology.

#OpenforSubmissions 📗Special Issue "Islet Biology and #Metabolism" Guest Edited by Dr. Melkam Kebede, Dr. Belinda Yau mdpi.com/journal/metabo… KebedeLab, Charles Perkins Centre, University of Sydney, Belinda Yau #Islets #Insulin

Super excited to see this study published! A team effort from labs in 4 cities across 3 continents! Biophysics Program University of Denver DU Natural Sciences & Mathematics @UofDenver Asensio Lab KebedeLab judith klumperman @JFitzpatrickWU

Fantastic collaboration!

Just woke up to the news that our JBC paper on sorting insulin granules by age made it to the “Best of 2020” list. As the first project we started from scratch and my first successful NHMRC project grant in the Kebede Lab this means a lot to me personally. jbc.org/best-of-2020

Our review on “Isolation and Proteomics of the Insulin Secretory Granule “ is now out on PubMed. pubmed.ncbi.nlm.nih.gov/33946444/

Outstanding group of EMCRS at the ADS Pincus Taft Young Investigator Session. Well done everyone. Congratulations to all the finalists. #21ADC

Huge journey of a study that could not have been accomplished without the amazing expertise of our co-authors - big shout out to all KebedeLab Sean Humphrey

In this review we discuss the key to better improving insulin secretion in metabolic disease may rely less on increasing the number of insulin granules released, and more on the quality of those secreted granules. doi.org/10.1016/j.bcp.…