Autoinducing peptides previously assigned as thiolactones are rather homodetic cyclopeptides. Now on ChemRxiv thanks to @BengtGless and Benjamin Bejder in collaboration with @HiIngmer lab. Thanks to LEO Foundation - LEO Fondet and DK Frie Forsk.fond for generous support💶. doi.org/10.26434/chemr… 1/3👇

Rearrangement of Thiodepsipeptides by S → N Acyl Shift Delivers Homodetic Autoinducing Peptides pubs.acs.org/doi/10.1021/ja…

.Christian Adam Olsen and coworkers UCPH Healthscience investigate the fate of thiolactone auto-inducing peptides (AIPs) from Gram-positive bacteria, which spontaneously rearrange to give homodetic cyclopeptides acspubs.co/QNbc50FqS9B

Today we celebrated 2021 papers from first authors @BengtGless and Carlos Moreno-Yruela in J. Am. Chem. Soc. and Nature Communications, respectively. Cake and bubbles. Thank you for the great effort from all coauthors and collaborators, including Benjamin Bejder @HiIngmer Clemens Schulte The Maric Lab

Big thanks to Hendrik Harms (@LabPless) and Fabrizio Monda (Christian Adam Olsen) for sharing their latest research during the CBP meeting today! Hendrik aims to shed some light on the enigmatic ion channel NALCN, while Fabrizio studies bacterial communication🦠Very exciting talks!👏

We are looking for an ambitious candidate to pursue their PhD degree in our lab. Exciting medicinal chemistry project related to auto-inducing peptides and inhibition of virulence in staphylococci. Deadline for application: January 9th, 2022. employment.ku.dk/phd/?show=1554…

This marks the end of 3 fantastic days at the #cell2cellbacteria22 conference hosted by Microbiology Society in Cambridge, UK. Great opportunity to meet with a lot of cool people and present our work on spontaneously rearranging autoinducing peptides in person.

Our latest review from the great Dr Severn ⁦@Mac_brown01⁩ Staphylococcus epidermidis and its dual lifestyle in skin health and infection | Nature Reviews Microbiology nature.com/articles/s4157…

Want to pursue a PhD in Chemical Biology? #UCPH_CBP at #UCPH currently has 3 open positions. Want to investigate how biomolecular condensates relate to health and disease in the CNS? Or develop peptides for the study of long-term effects of COVID? Apply before April 1.

I am happy to share that our manuscript on #thioester reactivity is now out in JACS Au. Big thanks to @SabrinaHelenaa, Benjamin Bejder, and my former PhD student and now co-corresponding author @BengtGless 👏 UCPH Healthscience Center for Biopharmaceuticals pubs.acs.org/doi/pdf/10.102…

Cross-species communication via agr controls phage susceptibility in Staphylococcus aureus dlvr.it/SwKplv

1 day Chemical Biology Symposium 7th June 2024 Copenhagen. Cracking line up. Alice Ting Alanna Schepartz The Muir Lab Kathrin Lang, Ben Davis, Dario Neri. Sign up now drug.ku.dk/calendar/event… Graciously supported by Novo Nordisk Foundation