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Presenting our #research from the Maximilian Reichert lab TU München on #PancreaticCancer #organoids and #heterogeneity at the Stem Cells and Cancer conference IRB Barcelona Thanks to the organisers for this great opportunity and wonderful event The BATLLE Lab Hans Clevers

And they do rotate ! Collective cell motion drive the self organization of mammary gland organoids structures nature.com/articles/s4156…

🎉Glad to see this one published: Microtubules tune mechanosensitive cell responses nature.com/articles/s4156… congrats to all authors and thanks Etienne-Manneville Lab and Shailaja Seetharaman for the opportunity to image beautiful migrating astrocytes 🔬

🔥NEW PREPRINT🔥 How are collectively migrating cells constrained by the curvature & topology of 3D systems? We discovered a collective velocity wave propagating in such a system & show that it emerges as a response of active matter to curvature 👉 arxiv.org/abs/2110.14614

Less than one week to submit an abstract! 👇

Make a dough and let it rise; observe it to self-organise. Don't forget to mention, though; it is an MT-actin dough. Our minds are very bright; we made a smart composite. We are writing history; the composite has memory. biorxiv.org/content/10.110…

Good stuff

New paper out in Nature Communications: polar patterns of filaments gliding *on a sphere*🌐nature.com/articles/s4146… A project from my PhD I love, with co-first Chiao-Peng and our old student Alice. Here a [long!] thread, with a bit of backstory, results, discussion and...cool movies!🧵1/22

Very nice..! And reminding of gliding systems with steric constraints!

Happy to see this fun collaboration out! Scroll down for more on the dual encoding of patterning and mechanics by morphogens, to preserve patterns throughout complex 3d morphogenesis!

Ondrej’s article appeared today in PNAS. I hope you enjoy reading this updated version.

If you ever need an overview of measurement methods of network #mechanics, here's a suggestion 😎 (Fig. 3 in our review) #Teaching Including work by BauschLab Kurt Schmoller on how actin networks with alpha actinin form bundles and stiffen after repeated shearing.

My first paper is out now. 🎉 We reconstitute the formation of VASP condensates on bilayers, which nucleate, polymerize and bundle actin filaments. The bundles grow by enhanced polymerization aligned to filaments. Thanks to @BleicherPhilip, Marco Payr 🇺🇦 and of course BauschLab.

(1/3) How do cells squeeze their large nucleus through tight spaces? In work led by Jeremy Keys and in collaboration with BiofluidicsLab (now at bioRxiv) we found that cells can push their nucleus by pressurizing their rear (video - left): biorxiv.org/content/10.110…

The next speaker of our #Future3DAM Cluster Conference 2024 is Andreas Bausch from TU München. He will present recent results on Structure Formation in Organoid Systems, explaining why Activity Matters. Register now! future3dam.org/registration-2… #organoids #researchconference

New preprint 🔥 my PhD swan song, with BauschLab @hamfaizi Petia Vlahovska Hagan Lab (+ Matt, Sarvesh Layne & Aparna) biorxiv.org/content/10.110… We put a microtubules+kinesin gel inside a GUV and... this happens: crazy fluctuations of a "cell" induced by a "minimal cytoskeleton"!

We study membrane and microtubules fluctuations using flickering spectroscopy, simulations and theory. The main message: the MTs push on the membrane and deform it, but are deflected by this soft boundary and hence "transport" the deformations along the membrane creating "waves"