📢 The 2024 Advanced San Servolo Epilepsy Course has been announced! The topic is "Presurgical investigation in the precision medicine era". ilae.org/congresses/20t… #ILAE #SanServoloAdvancedEpilepsy

Recent study on brain mosaicism in cortical malformations (epilepsy-linked astrocytic inclusions and chrom1q copy number gains) unveils post-zygotic rescue in most cell lines, except neural. Novel insights into brain-restricted high VAF variants. DOI: 10.1038/s41588-023-01547-z

Cell lineage analysis with somatic mutations reveals late divergence of neuronal cell types in human cerebral cortex

🌐 Discover how Antisense oligonucleotide-driven mTORC2 inhibition may be a game-changer in experimental and genetic mouse models of epilepsy. Special thanks to Mauro Costa-Mattioli and team for this nice collaboration! 👏 doi.org/10.1038/s41467… #ASO #mTOR #epilepsy #FCD

Dive into epilepsy research methods with our Basic & Translational Science Webinar Series! Join us for insights into models, EEG recording, drug discovery, and neurogenetics. 🗓️ Starting December 6th! Secure your spot for access to all sessions. Register in the link that follows

Excited to share our preprint on brain mosaicism in sporadic amyotrophic lateral sclerosis (sALS) and frontotemporal dementia (sFTD) that implicates surprising mechanisms. biorxiv.org/content/10.110…. 1/10

L'appel à candidatures du programme PhD international #CBRAINS est lancé pour 13 contrats doctoraux dont 5 mis à disposition par l’Institut du Cerveau - Paris Brain Institute. ⚠️ Clôture des candidatures le 29 janvier 2024. 👇 Pour en savoir plus : institutducerveau-icm.org/fr/actualite/c…

For Parisians😉

Thrilled to welcome the fantastic ISDN conference here in Montpellier 🤗 Looking forward to seeing you all there for great science and exciting discussions !

Don't forget to register for our 23rd April symposium on rare neurodevelopmental disorders with speakers amy mctague Sila Ultanir Albert Basson 🏳️‍🌈 Stéphanie Baulac Anna Jansen Gabriele Lignani eventbrite.co.uk/e/mrc-cndd-nih… Rare Disease Research UK CNDD| King's College #RareDiseaseDay2024

A subset of new TSC hits may act on ion channels or proximal mediators of neuronal excitability, rather than direct mTOR pathway inhibition. #TSC #epilepsy #mTOR

L'appel à projets 2024 de la FFRE est ouvert ! • Crédits de recherche : 1. « Comprendre ou soigner les épilepsies » : 60 k€; 2. « Epilepsie et Société » : 60 k€ • Bourse Valérie Chamaillard: 50 k€ • Syndromes FIRES/NORSE: 60 k€ fondation-epilepsie.fr, #FFRE

Because of #brainawarenessweek2024, we are thrilled to share that the 3rd edition of #BrainMosaic24 is set to take place in Leuven on the 10-11 October 2024. 📅 More info here: vibbio.tech/3TBDXBG See you there? #neurodevelopment #neurodegeneration #computationalanalysis

We've previously demonstrated age-associated accumulation of mutations in neurons. What about in other cell types, such as oligodendrocytes? By what mechanism & where in the genome? Out today in Cell Analysis by Joe Luquette in collaboration with ChrisAWalsh lab [1/]

Mutations in a small noncoding gene called #RNU4-2 are responsible for one of the most common of the #neurodevelopmental disorders caused by errors in a single gene. #Genetics #Neurodevelopment #IntellectualDisability Genomics England Mount Sinai Genetics nature.com/articles/s4159…

Senescent glia link mitochondrial dysfunction and lipid accumulation | Nature nature.com/articles/s4158…

Remarkable group of speakers at our upcoming Cold Spring Harbor Laboratory conference, including 👇 Arlotta Lab Gray Camp Silvia Cappello Simon Hippenmeyer Denis Jabaudon The Knoblich Lab Arnold Kriegstein Madeline Lancaster Laurent Nguyen Parmar Lab Debby Silver Lorenz Song and Ming Labs Pierre Vanderhaeghen

Please RT🗣️ I have a fully funded #postdoc position (see flyer) as well as a #ResearchAssistant position! If you are interested in #neurodevelopment, somatic #mosaicism and cell #lineages, please consider applying 🧠🧬 And feel free to contact me if you want to know more!!