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Congrats patty spears on such a well deserved award! 2023 Komen Research Advocacy Champion Award! UNC Lineberger #SABCS23 Susan G. Komen 👏👏

A recent paper from the @balkolab, led by Jamaal James and @bct255, indicates that EZH2 inhibition leads to enhanced MHC-II expression potentially through the improvement of chromatin accessibility at CIITA, the master regulator of MHC-II. doi.org/10.1136/jitc-2…

Tune in NOW for Breast Cancer Breakthroughs! Hear about the most exciting wins for patients announced at #SABCS23 from Komen grantees. Click here to watch: bit.ly/3X1yPW0

Proud to present this pre-print from my lab. Using single-cell multi-omics, 2 mice models, & pt samples, we found CXCR3 as a novel therapeutic target for ICI myocarditis critical for T-cell/macrophage crosstalk and perpetuation of cardiac inflammation biorxiv.org/content/10.110…

Excited to see the *official* version out!!! Great job by the editorial staff... It looks phenomenonal!

Super excited for next year's meeting! Only 290 days and counting (OK you got me... I didn't do the math I just guessed 😂)

From the latest issue— #NKG2A is a Therapeutic Vulnerability in #Immunotherapy Resistant MHC-I Heterogeneous Triple Negative #BreastCancer, by Brandie Taylor, Xiaopeng, BalkoResearchLab et al. bit.ly/49WMp43 Vanderbilt University Medical Center #TNBC

Rock.Star. Great talk with wonderful implications for the next generation of myeloid therapy in ccRCC. Can’t wait to see what you do next!

I am defending my dissertation next week on March 15th! Grateful for the mentorship by BalkoResearchLab ! DM me if you would like the zoom link.

This line up!!! Phenomenal. Society for Immunotherapy of Cancer Spring Scientific. Happening NOW!

So proud of this outstanding scientist and person Brandie Taylor defending her thesis today. A Susan G. Komen ASPIRE scholar, Cancer Discovery Journal for ImmunoTherapy of Cancer published author and all around superstar. Can't wait to see what the future holds!! @VUMCResearch Vanderbilt School of Medicine Basic Sciences

Komen grantee BalkoResearchLab presents his work on understanding and improving #breastcancer response to immunotherapy @ #AACR24. To learn more, check out the MBC Impact Series where he discussed his work: bit.ly/4cFtpsN

#ASCO24 Poster Session | Analysis of the sensitivity to endocrine therapy assay in the PALLAS adjuvant trial of palbociclib in HR+/HER2- #breastcancer (ABCSG-42/AFT-05/BIG-14-13). Otto Metzger Erica Mayer Dr. Michael Gnant Angie DeMichele, MD, MSCE, FASCO @ChristinaCurtis Christina Curtis BalkoResearchLab

Meet Immuno-oncology Senior Editor Justin M. Balko, PharmD, PhD. The BalkoResearchLab is focused on improving treatment outcomes in BC & other solid tumors, as well as the intersection between immunotherapy and tumor biology. Read the latest articles: bit.ly/3Lajnn3

As we better understand mechanisms that may drive ICI-myocarditis, we can think of more targeted therapies! Work by many individuals including DrJE-Salem @JimAllisonPhD Javid Moslehi BalkoResearchLab have led to ideas of targeting CD80/86, JAK-STAT signaling pathways, and T-cells! 6/

Next, @MargaretAxelrod talks about patient and tumor specific biomarkers in ici myocarditis👌 #gcos #gcos24 International Cardio-Oncology Society BalkoResearchLab Javid Moslehi

State of the Art: The Winding Road of Immune Biomarkers in Early Breast Cancer— Roberto Salgado, Justin Balko, and Priyanka Sharma will address this topic in this special session at #SABCS24 (December 10-13). Learn more: bit.ly/4h3tAR0 BalkoResearchLab Priyanka Sharma

State of the Art: The Winding Road of Immune Biomarkers in Early Breast Cancer—Roberto Salgado, Justin Balko, and Priyanka Sharma will address this topic in this special session at #SABCS24 (December 10-13). Learn more: bit.ly/3BjXxfB BalkoResearchLab Priyanka Sharma

Looks amazing! Great work Elizabeth Wescott!

New study 👉Dynamic single-cell systemic immune responses in immunotherapy-treated early-stage HR+ #BreastCancer patients. 🔓 pubmed.ncbi.nlm.nih.gov/40610460/ @MargaretAxelrod Sara Tolaney Dr. E Mittendorf BalkoResearchLab