Dr. Audrey Chagnot
@audreychagnot
Do you love Science? I made it my job! As a neuroscientist, I explore how vascular impairment in the aging brain triggers neurodegenerative diseases.
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19-03-2022 08:46:57
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UKDRI ECR Edinburgh seminars continue! Lovely talks from Alana from the Miron lab and Dr. Audrey Chagnot from the Montagne Lab UK DRI Early Career Researcher Network
Dr. Axel Montagne, PhD talking at the neuroinflammation conference in Manchester today. Montagne Lab is proud!
Myelin dance! White matter tracts - highways of the brain - are revealed in green in this 3D rendering of a fractional anisotropy map of the mouse #brain. On our way to create an atlas of these for our #MRI registration pipeline! Montagne Lab
Ghosts? No, vascular spectra! These density maps show how ageing affects vascular structure in the mouse #brain. Pericyte coverage is decreased and the vascular diameter slightly increased. Soon in our VasOMatic preprint! Montagne Lab
What an absolute joy to learn from the MRI legends Dr. Axel Montagne, PhD & Dr. Audrey Chagnot during the The CAJAL Advanced Neuroscience Training Programme for #Neurovascular function in #health and #disease with Réka Tóth Eline Luisa Binder in the beautiful Bordeaux🤩🤩🤩 Bordeaux School Of Neuroscience 🧠 University of Bordeaux
Prior work claimed that blocking dural lymphatic vessels could help treat #MultipleSclerosis and other CNS autoimmune diseases. Yet, a new University of Helsinki study in mice found that doing so yielded no notable change in symptoms or pathology. scim.ag/2hA
I had no idea for #FluorescenceFriday this week so I asked an AI (Craiyon) to draw me some cells. Well, it failed being scientifically correct but it accurately depicts the charming eeriness of the microscopic world. See you next week for real images from the Montagne Lab!
The Annual Conference of the British Microcirculation and Vascular Biology Society- June 29th-30th, 2023, Edinburgh. Abstract deadline in 1 week! British Microcirc. & Vascular Biology Society The Company of Biologists EdinUniREA
Arteriole, capillaries, venule - the three elements of microvasculature, ready for the show of #FluorescenceFriday ! Note how the cyan nuclei of arteries (left) are more elongated than those of venules (right), a useful tip when working at Montagne Lab !
Are they collapsed capillaries, bridging cells or tunelling nanotubes? In Montagne Lab we explore these strange advascular structures with innovative tools! Join us at @UU_University for CVB 2023 and discover more on my poster!
Spotted! If you have an eye for detail, you too might have encountered these 'bridges' of extracellular matrix hanging between two vessels. Do you want to know more? Stay tuned, Montagne Lab is on the go! We will present our findings at CVB 2023 in Uppsala!
A tightrope-walking cell? Embedded in vascular basement membrane, this bridging pericyte do the splits between two capillaries. Was it orphaned from its mother vessel or on the move to reach new horizons? At Montagne Lab, we're aiming to uncover it!
Do dural lymphatic vessels play a role in amyloid pathology? Maybe not… Fantastic talk by Salli Antila 🤩
After more drama than I would have liked, my poster is now up and ready to discuss #cbv2023 with Dr. Audrey Chagnot Dr. Axel Montagne, PhD The University of Edinburgh
Did you know that connexins roles extend beyond the gap (junctions) and are implied in the metabolic homeostasis of blood-brain barrier? Have look at our preview of Zhan, Meng et al.'s exciting study published in Neuron! authors.elsevier.com/c/1i5aX3BtfH5N… Montagne Lab