ICYMI 💥 in our #ChemSciPicks Chu Wang and Wei Qin of Peking University shed light on itaconate's antibacterial function by developing itaconate-based bioorthogonal probes to give a chemoproteomic profile of itaconations in Salmonella. Read in full ➡️ ow.ly/FBkI50E8lxr

My summary table comparing the new and highly effective anti-Covid pills, a vital step forward for prevailing over the pandemic No head-to-head trial to know about true comparative efficacy, but key differences in mechanism and other features

Happy to have publicly presented my PhD research for the first time! #NWOCHAINS2021 NWO Domain Science (Inactive)

Last chance to apply for a PhD position in my lab Science at Bath @BiosciencesBath University of Bath. If you have a passion for chemical biology and drug discovery this position is for you.

Electroaffinity labeling: a powerful new tool for target identification and Chemical Biology. Appearing today in ChemRxiv, a collaboration with brilliant Merck scientists: bit.ly/3B5eSEv

We are witnessing, literally watching live, Putin commit genocide on an industrial scale in Ukraine while the most powerful military alliance in history stands aside. It's impossible not to be emotional, but let us also be rational and focus our rage on the facts. 1/13

Paxlovid is a virus-directed pill, highly effective independent of variants. Now a pill that is host-directed, against the TMPRSS 2 receptor, also pan-#SARSCov2, with much potential, including as a preventive Rx, nature today nature.com/articles/s4158…

New Communication Article out now from Stephan M. Hacker, Angela Casini, Riccardo Bonsignore and first authors Claudia Schmidt & Michael Zollo @MedBioinorgChem Now included in our 2022 Emerging Investigators Collection Click here to read 🔽 rsc.li/3OT33rq

Check our collaborative synthesis of antibiotic #darobactin with Merck scientists! doi.org/10.26434/chemr…

Check out our latest paper in Chem describing a paired set of associative and dissociative bioorthogonal transformations enabling not only protein bioconjugation but also its rapid, traceless reversion! Chem doi.org/10.1016/j.chem…

#Teixobactin, isolated from 'unculturable' bacteria, is considered the first new 💊#antibiotic💊 in 30 years. But how does it kill bacteria? We show teixobactin uses a new mechanism that involves a double attack on the cell envelope Out nature nature.com/articles/s4158… #NMR 1/n

We urgently need solutions: science.org/doi/10.1126/sc…

BREAKING NEWS: The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”