Did you know that severe inflammation leaves a lasting impact on our blood stem cells? Excited to share our pre-print where we identified an HSC subset that remembers past inflammatory stress, which is linked to human aging and clonal hematopoiesis! doi.org/10.1101/2023.0… 1/

If you’re interested in studying how mutations alter gene regulation take a look at our new protocol for single-cell ATAC-seq with high sensitivity genotyping. #GTAC This is a detailed description of the method published earlier this year: doi.org/10.1016/j.stem…

NEW: Researchers from the Laboratory of Gene Regulation, led by Mira Kassouf & Doug Higgs, have identified a new type of non-coding DNA that helps to explain how our DNA is read. 👓🧬 Published today in Cell (Cell)! Read the full story here: bit.ly/3uQvb91

Delighted to share our latest work performed in close collaboration with the Nerlov lab. Hematopoietic stem cell heterogeneity and age-associated platelet bias are evolutionarily conserved | Science Immunology science.org/doi/10.1126/sc…

Excited to share our latest study in Journal of Clinical Oncology on improving risk stratification for older patients (≥60 yrs) with Acute Myeloid Leukemia (AML)! We developed a novel prognostic model: AML60+. #Leukemia #AML link: ascopubs.org/doi/full/10.12… 🧵1/9