
Amr Sawalha, MD
@asawalha
Professor and Director, Division of Rheumatology, UPMC Children’s Hospital of Pittsburgh, Director, Lupus Center of Excellence, University of Pittsburgh
ID: 37533741
03-05-2009 23:36:23
1,1K Tweet
687 Followers
381 Following


Excited to be part of this functional genomic effort unveiling new therapeutic targets for Takayasu arteritis! #vasculitis UPMC Children's Hospital of Pittsburgh UPMC Physician Resources Pitt Department of Pediatrics UPMC PittRheum Bowel disease breakthrough as researchers make ‘holy grail’ discovery theguardian.com/society/articl…


Very innovative and paradigm shifting work in APS. Thrilled to be part of this great effort by Dr. Tambralli, led by his outstanding mentor Jason S Knight

Just published: The first genome‐wide association study in primary antiphospholipid syndrome. New pathogenic insights revealed through genetics UPMC Physician Resources Pitt Department of Pediatrics PittRheum acrjournals.onlinelibrary.wiley.com/doi/abs/10.100…


🔬🧬 New study of a rare #lupus case in Turner syndrome suggests a link between X-chromosome dosage and lupus #epigenetics. Could this explain sex-bias in lupus and the low lupus incidence in Turner syndrome?🤔UPMC Physician Resources PittRheum Pitt Department of Pediatrics sciencedirect.com/science/articl…


🔬Pediatric #lupus in Western PA, US 🇺🇸and Turkey 🇹🇷! Turkish patients have earlier onset and more renal involvement. Damage Index scores are similar across cohorts. Global findings for better #SLE care! 🌍UPMC Physician Resources Pitt Department of Pediatrics PittRheum journals.sagepub.com/doi/10.1177/09…

A new study led by Dr. Ajay Tambralli, in collaboration with colleagues from Michigan Medicine and University of Pittsburgh, shows the promise of leveraging metabolism as a treatment approach in #APS. Jason S Knight Yu (Ray) Zuo Jordan Schaefer Lyssiotis Lab Amr Sawalha, MD michiganmedicine.org/health-lab/cou…

📝ACR_Journals are dedicated to fair representation and respect. Our guidelines emphasize accurate reporting and thoughtful terminology. Let’s ensure our research is inclusive and unbiased, with clear, precise language that honors all individuals. 🌍🔬 acrjournals.onlinelibrary.wiley.com/doi/10.1002/ar…

Our latest publication showing that inducible deletion of epigenetic regulator Ezh2 in CD4+ T cells prevents interstitial nephritis in lupus models iScience UPMC Physician Resources UPMC Children's Hospital of Pittsburgh PittRheum Pitt Department of Pediatrics cell.com/iscience/fullt…

Our recent paper unravels the impact of hydroxychloroquine at a single-cell level in vitro and in #lupus. Enhancing CD8+ T cytotoxicity might underlie its protective effect against viral infections in #lupus Pitt Department of Pediatrics UPMC Physician Resources PittRheum authors.elsevier.com/sd/article/S08…


Our rheumatology fellow Mehmet Hocaoglu, MD first-author publication in A&R showing ANA production is primarily determined by non-genetic factors independent of lupus genetic risk PittRheum Pitt Department of Pediatrics PittDeptofMed UPMC Physician Resources ACR_Journals acrjournals.onlinelibrary.wiley.com/doi/10.1002/ar…


Our latest publication on the genetics of Takayasu arteritis! We reveal new functional genetic insights, genetic risk score calculations, and a practical approach to communicating genetic risk to patients. acrjournals.onlinelibrary.wiley.com/doi/10.1002/ac… PittRheum UPMC Physician Resources Vasculitis Foundation




We developed an Environmental Risk Score (ERS) for SLE —showing it predicts risk on par with the Polygenic Risk Score (PRS). Combining both improved prediction. 📄 First-author paper by our rheumatology fellow Mehmet Hocaoglu, MD in Journal of Autoimmunity! sciencedirect.com/science/articl…


Thanks to #TheRheumatologist for highlighting our efforts to better understand the genetic basis of Takayasu arteritis the-rheumatologist.org/article/new-an… UPMC Physician Resources Vasculitis Foundation ACR_Journals PittRheum Pitt Department of Pediatrics #vasculitis #Takayasu
