Just published concurrently with an #AACR24 poster— ZNF397 Deficiency Triggers TET2-driven Lineage Plasticity and AR-Targeted Therapy Resistance in #ProstateCancer, by Yaru Xu, Ping Mu 🇺🇦 et al. bit.ly/3Ucp3C8 PCF Science UTSW Simmons Cancer Center AACR

It is all about balance - great work from Malladi Lab - UTSW #AACR24

Take home messages from Dr. Mikala Egelbad on #AACR24 basic cancer research. Bottom line: ChatGPT is not ready to replace human scientists

The OncoAlert 🚨ROUND UP Covering April 5th-12th, 2024 REGISTER at OncoAlert360.com OR oncoalert.m-pages.com/nhMpwe/oncoale… Discussing: ✅ U.S. FDA 🇺🇸approval trastuzumab dx fda.gov/drugs/resource… ✅ Durvalumab in🫁 Small Cell #LungCancer astrazeneca.com/media-centre/p… ✅ Alina out

🔥Check out this paper from the Chan Lab Isaac Chan, MD, PhD in Cell Reports Medicine ➡️single cell seq data to define #IntratumorHeterogeneity and predict immune cell interactions in #BreastCancer ➡️the InteractPrint score predicts response to #immunotherapy UTSW Simmons Cancer Center doi.org/10.1016/j.xcrm…

T-DXd is the premier ADC for the treatment of pts with HER2+ MBC BrMs. The analysis underscores the pressing need to investigate T-DXd in HER2-low BrMs, active HER2+ BrMs across solid tumors, and LMD. We suggest default inclusion of pts with BrMs into clinical trials of ADCs.

A new study shows that using a PRMT5 inhibitor with other therapies overcomes drug resistance in tumors. This blocking gene may halt growth of #breastcancer cells and could lead to new treatment strategies. Carlos L. Arteaga, M.D. Dr. Ariella Hanker UT Southwestern Medical Center bit.ly/3UGGAmA

#UTSW researchers developed a tool that can accurately predict which patients with #breastcancer will respond to immunotherapies by examining which genes were turned on and off in a mix of cell types from their biopsies. Isaac Chan, MD, PhD Heather McArthur, MD, MPH Sangeetha Reddy bit.ly/4a0LP4C

One day until the Wendy & Emery Reves International Breast Cancer Symposium! Register now at the link below for this exciting event taking place on May 3-4. See you there! Registration link: events.utsouthwestern.edu/event/wendy_em… UTSW Simmons Cancer Center Carlos L. Arteaga, M.D. Debb Farr #bcsm #breastcancer

The Jewish students of Columbia have come together and written their earnest plea for a safer campus. They do not ask for support for Palestinians to end or for all criticism of Israel to be quieted. What they want, and what we should all want, is simply an end to the

Registration is now open for the annual invasive #lobular breast cancer symposium (ilcsymposium.com) which will take place in Leuven, Belgium, this year on September 23-25! Register now as places are limited. OncoAlert

Today is an exciting day for the Der lab! Check out our two papers dissecting the KRAS-ERK regulated transcriptome and ERK regulated phosphoproteome in KRAS mutant cancers. Channing Der Clint Stalnecker Science Magazine UNC Lineberger science.org/doi/10.1126/sc… science.org/doi/10.1126/sc…

🙌Hey UTSW Simmons Cancer Center UTSWCancerBio UTSW Hematology & Oncology UTSW Science UTSW Department of Pathology Mol Biology Dept UTSW Lyda Hill Department of Bioinformatics, don't miss our next #KomenBreastCancerForum featuring our very own Dr. Sihan Wu Sihan Wu 吴思涵 Children’s Research Institute at UT Southwestern June 26! 🤯Prepare to have your mind blown hearing about #ecDNA in cancer🧬

Excellent opportunity for patient advocates to attend SABCS and to engage with other advocates, clinicians, and researchers. You might even meet your bestie, like I did when I completed the program with Julia Maués in 2018 :)

🙌Hey UTSW Simmons Cancer Center UTSWCancerBio UTSW Hematology & Oncology UTSW Science UTSW Department of Pathology Mol Biology Dept UTSW, don't miss our next #KomenBreastCancerForum featuring Dr. Heather Parsons Heather Parsons Dana-Farber *in person* tomorrow 7/24! #ctDNA #liquidbiopsy #precisiononcology 🩸🧬

🙌Hey UTSW Simmons Cancer Center UTSWCancerBio UTSW Hematology & Oncology UTSW Science UTSW Department of Pathology Mol Biology Dept UTSW, don't miss our next #KomenBreastCancerForum featuring UTSW's own Dr. Chuo Chen Weds, Aug 21! #proteindegradation #PROTAC #FGFR #precisiononcology

Today!

A typical paper today

Huge conrats to Qing Zhang and Malladi Lab - UTSW! So well deserved!! UTSW Simmons Cancer Center

🙌Hey UTSW Simmons Cancer Center UTSWCancerBio UTSW Hematology & Oncology UTSW Science UTSW Department of Pathology Mol Biology Dept UTSW, don't miss our next #KomenBreastCancerForum featuring Dr. Huiping Liu Huiping Liu Northwestern Feinberg School of Medicine *in person* 9/18! #breastcancer #metastasis #CirculatingTumorCells Host Qing Zhang