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Just out! #letstalkhistiocytosis While BRAF VE1 is a sensitive antibody clone for histopathologic workup, sometimes we need to exercise caution in interpretation; molecular confirmation is always encouraged. link.springer.com/article/10.100…

A great start on a Saturday morning at the inaugural rare disease run organized by UAB Medicine. Such an important initiative and an honor to be a part of it! Together we raise awareness for a better tomorrow for all patients with rare diseases.#letstalkhistiocytosis #raredisease

Congratulations to our prior fellow, now assistant professor Savanah Gisriel, MD, MPH on the new manuscript standardizing marrow diagnoses for MDS. Thank you Amer Zeidan MBBS,MHS ‏عامر زيدان for the vision and International Consortium for MDS (icMDS) for coming to clinical, pathologic, inter-institutional consensus. pubmed.ncbi.nlm.nih.gov/40059041/

I posted a poll yesterday asking you to choose ONE test from 4 options that would be most helpful for distinguishing between iron deficiency and thalassemia trait. Most answered the Mentzer Index. My preference would be a good old fashion comparison with CBC from 20 y ago 😀

#letstalkhistiocytosis A very important podcast about updates in histiocytosis! tune in to learn more; Gaurav Goyal Jithma Abeykoon, M.D. Aldo A Acosta Medina Histiocytosis Assoc Listen to "Episode 077 - MEK Inhibitors in ECD" by Beyond the Diagnosis creators.spotify.com/pod/show/histi…

PAROXYSMAL NOCTURNAL HEMOGLOBINURIA I posted a poll yesterday asking what the most likely presentation was of a patient with labs c/w hemolysis and hemoglobinuria. DVT was the least popular answer but the correct one!

Very excited to share our latest research article published with Springer Nature in Nature Communications. We show that in early #MDS, NK cells share mutations with the malignant clones, becoming dysfunctional and failing to eliminate aberrant stem cells. This leads to immune evasion and

Calling on #pathology #board takers - Chicago Board Review Series Registration closing soon !! Sanjay Mukhopadhyay Jerad Gardner, MD Andrew Bellizzi 🇺🇦 Kamran Mirza MD PhD - کامران مرزا Xiaoyin "Sara" Jiang, MD (She/Her) Esther Diana Rossi Gladell Paner, MD Virtual Pathology Student Interest Group PathElective Vikram Deshpande Munita Bal Register here: chicagoboardreviewseries.org

ISOLATED NEUTROPENIA - CLASSIFICATION

RELATIONSHIP MCH, MCHC and MCV Ignore the MCH! ... it is simply a marker for the MCV (and to a lesser extent the MCHC) It does not figure in ANY classification of anemia Turns out, however, that the MCH is useful for hematology experiments in space. Why is that?

An absolutely important thread for every medical student in early years of training! Learning step 1 is not just about passing the boards but to improve, improvise & learning to apply in real time practice! The practice of medicine goes beyond textbook knowledge! #Medstudent

“Limited” biopsies often hold the 🔑 to the dx - pitfall of labeling . Here in a tiny bit of cortex are “crystals” within mononuclear CD68 positive cells. Great EM team captured dazzling crystals. IF pronase -be Crystal storing histiocytosis. DD: lymphoma

What a great way to spend the Saturday! A fantastic nerdy hemepath day with lots of interesting cases. Never a dull day in the practise of Hematopathology 🥳Thanks to Michael A. Linden, MD, PhD and team for the incredible organization and for hosting this year ☺️ #RCMHemepath2025 #umnhemepath

#letstalkhistiocytosis #RCMHemepath2025

#letstalkhistiocytosis #RCMHemepath2025

Join us at the 2025 SH-EA4HP Workshop. Sept 4-6, in Cincinnati, OH. You will see fascinating cases with renowned speakers presenting the latest in pediatric and young adult #Hemepath. Make sure to register! More information in SH-EAHP 2025 Workshop#SH25 #leusm #lymsm

Peripheral Blood Flow Cytometry-based Definition of Plasma Cell Leukemia. @mayomyeloma Leukemia nature.com/articles/s4137…

Here is the group photo of the doctors who participated in the 2025 ECDGA Medical Symposium in Barcelona. erdheim-chester.org/medical-expert…