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I met Alan and Mart this summer at the Lipoprotein Metabolism GRC and we had a great time comparing our data. They published a beautiful paper here describing apoB bound to the LDL receptor. Pairs perfectly with our paper released on the same day. nature.com/articles/s4158…

Thanks for highlighting our paper Eric Topol!

Pretty badass actually. If only Walter White had been a virologist and not a chemist, so much drama could have been avoided

Now that AlphaFold has tackled biology’s greatest challenge, scientists can turn to even bigger questions magazine.hms.harvard.edu/articles/did-a…

Cholesterol-wrapping lipoprotein gets a closer look cen.acs.org/analytical-che… via C&EN (Chemical & Engineering News) nice article highlighting our recent #apoB structure and the complementary work from the NIH NHLBI team!

Thrilled that our atomic model of sperm doublet microtubule is now published Revealing axoneme ATP regenerating system, anchoring of signalling kinases and dyneins pre-powerstroke conformation Great collaboration with Rui Zhang and Alan Brown! nature.com/articles/s4158…

the craziest glycoprotein structures you'll ever see! pnas.org/doi/full/10.10…

The structure of bad cholesterol comes into focus nature.com/articles/d4158… A nice news piece from Nature on our structure and the LDL-r complex structure from NIH NHLBI !

all that work to make a GFP with the same structure that is not as good...the 500M of evolution thing seems like is a slick marketing slogan. If the tech is so great, why not go after a novel function? Maybe I'm missing something

The open access version of our ApoB structure paper is now live nature rdcu.be/d7uCe

"The molecular structure of LDL has finally been elucidated" - rdcu.be/d7OfC News and Views piece online today in Nature Reviews Cardiology

A protein at the heart of heart disease showme.missouri.edu/2025/a-protein…

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Hypothesis generation and testing is a critical capability for AGI imo. Super excited about our AI co-scientist and other AI for Science work which are important steps towards that. We're on the cusp of an incredible new golden age of AI accelerated scientific discovery.

ApoB is the PDB molecule of the month! Looking good 🤩 doi.org/10.2210/rcsb_p…

April's Molecule of the Month: Apolipoprotein B-100 and LDL Receptor Insights into how LDL is removed from the bloodstream pdb101.rcsb.org/motm/304