Xiongyi Huang-JHU Biocatalysis
@xiongyih
Biocatalysis, Bioinorganic Chemistry, New Enzyme Evolution
ID:287977766
https://xhuanglab.com/ 26-04-2011 01:15:19
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I would like to express my gratitude to my collaborators, Marc Garcia Borràs and Prof. Yunfang Yang from Zhejiang University of Technology, for their valuable contributions to this project.
Excited to share our work on engineering protoglobins to catalyze the challenging formation of cis-trifluoromethyl substituted cyclopropanes. I initiated this project while I was at Caltech and am grateful for Frances Arnold letting me be the corresponding author of this paper.
Congratulations to JHU Chemistry professor Xiongyi Huang (@xiongyih) for being named a 2021 Packard Foundation fellow. 🎉'Our lab is working on some very challenging transformations to incorporate into nature.' hub.jhu.edu/2021/10/14/xio…
Incredibly honored to be part of the 2021 #PackardFellows Packard Foundation This was made possible with the hard work of my group @ Anthony Huls Jinyan Zhao Qun Xin yuan Ji Zhenhong Chen @jamesgzhang. I am grateful to my previous mentors and my colleagues JHU Chemistry for their support.
Check our new application of SAMDI for enabling #highthroughputscreening of #enzymes in #directedevolution ! Congrats to Adam and our collaborators Dan, Xiongyi, and Frances Arnold on their publication in J. Am. Chem. Soc.!
Xiongyi Huang-JHU Biocatalysis Adam John Pluchinsky
pubs.acs.org/doi/10.1021/ja…
This time we taught our enzymes to introduce fluorine-containing groups to molecules via selective C-H functionalization. Check out our newest C-C bond-forming P450s on J. Am. Chem. Soc.! Frances Arnold Xiongyi Huang-JHU Biocatalysis
pubs.acs.org/doi/10.1021/ja…
It is so honorable to contribute to the 30th anniversary issue of Synlett! Thanks to all the co-workers in this work Xiongyi Huang-JHU Biocatalysis ExaZhang Jennifer Kan, Andrew Zhou and of course, Frances Arnold and Xin Hong!
Our recent work on enzymatic synthesis of trifluoromethylated organoboranes is highlighted in the March issue of Nature Catalysis! nature.com/articles/s4192… Frances Arnold Marc Garcia Borràs Jennifer Kan @MorphingKernal Ken Houk
Newest results from Xiongyi Huang-JHU Biocatalysis and Marc Garcia Borràs who bring #fluorine (CF3) to organoborons with #enzyme and #directedevolution . Structurally diverse diazos accepted, and cool explanation of how!