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Today in J. Am. Chem. Soc., we report our new enzymatic strategy for C-terminal protein and peptide engineering. We found that an asparaginyl ligase can irreversibly incorporate diverse nonpeptidyl amines at a C-terminal Asn. CIPPS pubs.acs.org/doi/10.1021/ja…

Enzymatic C-Terminal Protein Engineering with Amines #protein #engineering pubs.acs.org/doi/10.1021/ja…

Enzymatic C-to-C Protein Ligation (Durek) UQ Chemistry and Molecular Biosciences #openaccess onlinelibrary.wiley.com/doi/10.1002/an…

New 🔥hot paper🔥 in Angewandte Chemie! We design and characterise a C-terminal reversed mimetic of an N-terminal asparaginyl ligase substrate. This mimetic enables direct enzyme-catalysed protein and peptide C-to-C ligation. Institute for Molecular Bioscience UQ News CIPPS onlinelibrary.wiley.com/doi/10.1002/an…

A Guide to Decentralized Biotech "In an ideal world, we could test hundreds of ways to get from “bench to bedside,” mixing and matching the components...for maximum efficiency." future.a16z.com/a-guide-to-dec… #desci #biotech

What a wonderful and productive few days! Thank you to everyone who made #CIPPS2022 so special! Watch this space for some very exciting science 🧪 🧬🌱🕷🐨💊🫖🎉

Delighted to share our #AusPeptide2022 conference photo! With thanks to our sponsors! Mimotopes Shimadzu Oceania Scientific Instruments Division ACS_Omega @BMGLABTECH Davies Collison Cave GenScript IJMS MDPI AusPep MedChemExpress James & Wells PerkinElmer Proteomics-Int SCIEX Communications Biology Iris Biotech GmbH

The Australian Peptide Conference sponsored poster prize winner Tristan Tyler Enhanced asparaginyl endopeptidase peptide and protein labelling via selective nucleophile quenching

Congratulations Tristan Tyler on winning the Poster Prize at #AusPeptide2022 🎉 The Craik group representatives have enjoyed all the exciting presentations and discussions AusPeptide 🥳 @researcherconan Yen-Hua Crystal Huang Nicole Lawrence Abhishek Bajpai, PhD

A very big congratulations to our (poster) award-winning CIPPS students! 🥳🎉 Tristan Tyler (The Craik Group) Institute for Molecular Bioscience Kimberley Biggs (Glenn King) Dhanya (Malins Lab) ANU Research School of Chemistry Junming He (Christoph Nitsche) Well done all! #AusPeptide2022

Congratulations to our PhD students Tristan, Linh and Jing for their exciting Three Minute Thesis presentations! So proud of you 😍 #3MT Institute for Molecular Bioscience UQ News CIPPS Tristan Tyler received People's Choice Award 👏 We think Drizzy will also give you his vote 😉

Congratulations Alexander Yu for winning IMB's Three Minute Thesis (3MT)! He will now go on to compete in the All Institutes Finals. Congratulations also to runner up Patricia Essebier and People's Choice winner, Tristan Tyler! #3MT #phd #uniofqld

Check out our new paper for site-specific labeling proteins and building defined Ub/Ubl-protein conjugates using a plant Asp-endopeptidase. Great effort by Max Fottner @jhmgrtnr Maximilian Gantz RaMue and TimonNK! Congratulations to all!👩‍🔬👨‍🔬🤩🙌🥳

Truly thankful for the opportunity to present my work from The Craik Group and CIPPS at the 36th European Peptide Symposium. It has been such a pleasure to discuss science with talented individuals from around the world. #EPS2022 #36EPS #12IPS

Peptide Family ! Great to have met with some other CIPPS researchers this week at the 36th European Peptide symposium in Barcelona ! European Peptide Society CIPPS The Craik Group Malins Lab Glenn King Kate Jolliffe Payne Research Group

Christmas in the Craik Group 😂 The Craik Group

Happy to announce my paper "Repurposing a plant peptide cyclase for targeted lysine acylation" has finally been published in Nature Chemistry. Thanks to everyone The Craik Group for their contribution, it was a pleasure working on this project! rdcu.be/dISZw