🔈 Closing remarks from Maria Garcia Alai about the EMBO course “ Membrane protein expression, purification and characterisation 3 (mPEPC3)” in EMBL HH/CCSB. A lot of work and commitment to make this course a success along with an amazing group of students! 👏🏽🧪📚 #EMBOPEPC

It is a wrap 🙌🏽 ! Thank you so much to academic and industry speakers, tutors and participants who attended the EMBO practical course mPEPC3 in EMBL Hamburg/ CSSB. We had 8 days of lectures, practicals and networking on the membrane protein field 📚🦠🔬 👏🏽 to our sponsors!

Thank you to everyone who joined us for #EMBOPEPC last week in Hamburg! 💫 It was a great opportunity to dive deeper into structural studies of membrane proteins. We hope you enjoyed the course and until next time! 👋 Stay updated on future courses: ➡️ embl.org/events/

We are looking for ARISE applicants to join our facility. Contact us!

We are currently recruiting predoc candidates at EMBL Hamburg! Contact us X-Ray Imaging Team @EMBL, Jan Kosinski and SPC Facility & Garcia-Alai Lab @EMBL Hamburg @EMBL

Thanks again to our SAB members Wai-Hong Tham, Olivier Neyrolles Friedrich Forster, Edda Klipp, Ilaria Ferlenghi and Hans-Georg Kräusslich for joining us for a great two day meeting!

Working with dimers and Circular Dichroism? We updated our Chirakit tool with more unfolding models (spc.embl-hamburg.de/app/chirakit). All feedback is welcome! :) The image below shows a global fitting (N2 <-> I2 <-> 2U) of data from Figure 3A, Felipe Montecinos-Franjola et al., 2012.

🔍 Today we had the pleasure of having LUMICKS at EMBL Hamburg in CSSB Daphne Jurriens introduced us to dynamic single-molecule microscopy using DNA - protein interactions along with other applications in phase separation, protein folding and dynamics! 🔬🧬

More updates to our CD tool (spc.embl-hamburg.de/app/chirakit) 🥳 - CD spectra prediction from protein structures (Nagy, et al. 2019) - Bayesian secondary structure estimation (Nagy, et al. 2021) - Thermal unfolding for helical peptides (Zavrtanik, et al., 2024)

Federico Agustín Vignale is presenting our work on Extreme Microbial Ecosystems at the Planetary Biology retreat EMBL -a multidisciplinary study with several collaborators, including the X-Ray Imaging Team @EMBL team.

🔊 I am delighted to share our latest paper “Subtleties in Clathrin heavy chain binding boxes provide selectivity among adaptor proteins of budding yeast” Great collaboration with our colleagues from the CSSB @SkruznyMichal Our publication ⬇️ rdcu.be/dZujI

Glad to be present at the 32nd Protein Structure Determination in Industry (PSDI) 2024 conference, taking place in Paris from 10-12 November. 🇫🇷 Looking forward to great discussions on how we can help you to tackle your biophysics and structural studies at EMBL Hamburg 🦠🧬

Scientists from EMBL Hamburg and CSSB have provided key insights into the cellular process of clathrin-mediated endocytosis. They revealed details on specialised functions of two adaptor proteins involved in the process. embl.org/news/science-t…

Join CSSB! Our Protein Production and Sample Preparation and Characterization core facilities are looking for a technical assistant to develop cross -facility workflows. More information: lnkd.in/ezZXiDtV

Follow us in Bluesky 🦋 🌅 @spcembl.bsky.social

New preprint alert 🔔 ! New insights into the clathrin-mediated endocytosis machinery! Sla2 emerges as a central hub interacting with Clathrin Light Chains and the Pan1/End3/Sla1 complex. Read the full study ⬇️ : doi.org/10.1101/2024.1…

📣We are looking for an enthusiastic postdoctoral candidate to work on an interdisciplinary project combining Biochemistry of extremophyles and Structural Biology! 🤝The position will be held in collaboration with Donato Giovannelli and Vikas Trivedi 📩[email protected]

We are only posting🦋! Follow us in Bluesky @spcembl.bsky.social

We are looking for an enthusiastic postdoctoral candidate to work with SPC Facility & Garcia-Alai Lab @EMBL Hamburg @EMBL and myself on an interdisciplinary project combining Biochemistry of #extremophile and #StructuralBiology. The position will be held at EMBL Hamburg in collaboration with myself Unina Federico II #postdoc