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Excited to share our new CLASH platform published at Nature Biotechnology! mass knock-in engineering in human T cells and beyond nature.com/articles/s4158… Yale School of Medicine Yale Department of Genetics Yale Cancer Center Yale West Campus Nature Biotechnology

Strongly support colleague and friend Dr Pat LoRusso from our cancer center for AACR president run! Go Pat! Thank you for your great service and contribution to the field and community Yale Cancer Center

Our new Monkeypox mRNA vaccine! Yale Department of Genetics Yale School of Medicine Yale Ventures Yale West Campus Zhenhao Fang nature.com/articles/s4142…

Immunogenetic metabolomics reveals key enzymes that modulate CAR T-cell metabolism and function aacrjournals.org/cancerimmunolr… Our lab's new work. Yale School of Medicine Yale West Campus Yale Department of Genetics Yale Cancer Center See also Ping Wang lab and Crystal Mackall lab's work.

Scientists at Yale's Systems Biology Institute have developed a ‘MAJESTIC’ gene delivery and immune cell engineering technology with the potential to advance cell therapies for cancer and other diseases bit.ly/Chen-majestic Sidi Chen Yale University Yale School of Medicine Nature Biomedical Engineering

Our work at Nature Immunology on a new way of cell therapy engineering. Proud of 1st author Ariel & team. Special Tx to Dr. Levchenko. Yale University Yale Department of Genetics Yale Cancer Center Yale West Campus Yale Center for Biomedical Data Science (CBDS) Yale School of Medicine nature.com/articles/s4159…

🤩🤩 Beautiful cover art Nature Biotechnology depicting new paper led by Xiaoyun Dai Sidi Chen lab 👇🏽👇🏿👇

We are thrilled to announce the official launch of Genome Editing in Cancer and Immunology, a specialty section journal led by Prof. Sidi Chen of Yale School of Medicine. Ready to receive your submissions. Discover more here: fro.ntiers.in/GECancerandImm…

Congrats for Ariel Xiaoyu Zhou my postdoc in Yale Cancer Center Yale Department of Genetics Yale School of Medicine Yale West Campus Yale Center for Biomedical Data Science (CBDS) getting an NIH/NCI K99/R00 award starting this month to study T cells and engineer next generation CAR-T cell therapy for cancer!

Our new high fidelity enhanced AsCas12a/Cpf1 transgenic mice after five years of work. Generated by Matt Dong and colleagues here in lab at Yale Department of Genetics Yale Cancer Center Yale School of Medicine Yale West Campus Anyone who want to try them out feel free to please contact us. biorxiv.org/content/10.110…

“Building a community and paying attention to that community is the essence of getting things done.” Today #JameelClinic Advisory Board Chair and Nobel laureate Phil Sharp celebrated the 50th anniversary of his lab, “The Sharpies” — half a century of sharp minds!

Our first in vivo primary NK screen that discovered new NK cellular checkpoints. Kudos for team for their 5 years of work. nature.com/articles/s4158… Yale Department of Genetics Yale School of Medicine Yale West Campus Yale Cancer Center Yale Center for Biomedical Data Science (CBDS)

Honored to serve on the panel of #AI for drug discovery in biomedicine at #AIME 2024 Utah. Very stimulating discussions on future of medicine, challenges etc, with experts and audience. Yale Center for Biomedical Data Science (CBDS) Yale Data Science Yale Department of Genetics Yale Cancer Center Yale Ventures

Our team’s new work “MUCIG” cancer therapy - Multi-target approach counters tumor growth in several cancers | Yale News Feng Zhang ⁦Ryan Chow⁩ Guangchuan Abrasive Technology Wang ⁦Yale University⁩ ⁦Yale Cancer Center⁩ ⁦Yale Department of Genetics⁩ ⁦Yale West Campus⁩ news.yale.edu/2025/01/16/mul…

Our new “MUCIG” therapy @FF Zhang ⁦Ryan Chow⁩ @GW ⁩ ⁦Yale Cancer Center⁩ ⁦Yale Department of Genetics⁩ ⁦Yale West Campus⁩ Multiplexed inhibition of immunosuppressive genes with Cas13d for combinatorial cancer immunotherapy | Nature Biotechnology nature.com/articles/s4158…

Our lab generated 4 new lines of Cas12a transgenic mice and demonstrated utility in immune engineering, tumor modeling, and genetic disease treatment. Around to share w the field & community! Yale School of Medicine Yale West Yale Department of Genetics Yale Center for Biomedical Data Science (CBDS) Also Monte Winslow's Lab nature.com/articles/s4155…

.Sidi Chen co-chairs a symposium highlighting the transformative field of adoptive cell therapies for #cancer treatment #AACR25 with Dr. Daniel Powell Penn Medicine AACR Smilow Cancer Hospital Yale West Campus Yale Department of Genetics

Excited to present our new work on multiplex immune gene therapies for cancer @ASGCT 2025 New Orleans Yale School of Medicine Yale Cancer Center Yale Department of Genetics Yale West Campus