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A great recap of all seasons from the "Denisova-Modern Human" romance series by Linda Ongaro and Emilia Huerta doi.org/10.1038/s41588…

In absolutely perfect timing for #ASHG24 I am so pleased to announce the labs second manuscript that was entirely conducted Human Technopole. Here we showcase the power of diffusion autoencoders for phenotyping time resolved cardiac MRIs in 70k subjects. medrxiv.org/cgi/content/sh…

Want to visualize between-group comparisons with added statistical insights? The ggbetweenstats() function from the ggstatsplot package is designed for exactly that. It combines violin and box plots to show group distributions while seamlessly including statistical test results

Congratulations Eugenia D'Atanasio 🧬🦴 amazing work

cell.com/ajhg/fulltext/…

very excited to share the last chunk of my PhD work, now available on bioRxiv! in this work, we explore how cis-regulatory variation and gene-environment (GxE) interactions influence immune response diversity directly in a cohort of hospitalized COVID-19 patients 1/n

Biobanking with genetics shapes precision medicine and global health | Nature Reviews Genetics nature.com/articles/s4157…

Kicking off the new year, our paper by Leo Speidel et al. is out describing what to me is a breakthrough in ancient genomics. By using genealogies to study ancestry we can get much more resolution to study finer-scale history. We call this method Twigstats.

🎙️ Per Tgr Leonardo, Nicole Soranzo racconta il progetto Genome of Europe, il più grande progetto genomico finanziato dall'UE, per promuovere prevenzione e cure personalizzate. (da min 11.20) rainews.it/tgr/rubriche/l…

Congratulations Lehti Saag!

Our new paper is out! Congrats to the whole team, especially the staff and students Bournemouth Uni who have been excavating this incredible site for 15 years (with much more left to uncover!) Widespread matrilocality in Iron Age Britain - Up Na Mná :) rdcu.be/d6mb0

One week to the abstract submission deadline for SMBE 2025, Beijing 20-24 July! smbe2025.scimeeting.cn Anastasia Ignatieva and I are organising a symposium on popgen through time: using ARGs, aDNA, or otherwise to understand the evolutionary processes that shape genomes through time.

🚨🚨Spoiler Alert!🚨🚨 Next month, I'll present at the Meeting of the American Association of Biological Anthropologists (AABA) the study that was published yesterday in the 𝘈𝘮𝘦𝘳𝘪𝘤𝘢𝘯 𝘑𝘰𝘶𝘳𝘯𝘢𝘭 𝘰𝘧 𝘏𝘶𝘮𝘢𝘯 𝘎𝘦𝘯𝘦𝘵𝘪𝘤𝘴. 🫣👇🏽 cell.com/ajhg/fulltext/…

PANE: fast and reliable ancestral reconstruction on ancient genotype data with non-negative least square and PCA genomebiology.biomedcentral.com/articles/10.11… 🧬🖥️🧪 #Rstats 📦 github.com/lm-ut/PANE

Great meeting yesterday with Francesco Lescai team and Alberto Riva team to discuss Nextflow and nf-core patterns in bioinformatics and future training initiatives to spread the use of workflows in Human Technopole and in the Italian community.

Our perspective on pangenomes in diverse populations and their critical role in advancing Precision Medicine nature.com/articles/s4159…

Happy faces for the Human Technopole guys after 3 days of pipelining and Nextflow coding and some approved contributions during our first nf-core Hackathon! Thanks Francesco Lescai for hosting the event in Pavia!

This podcast is fear mongering at its worst. I will make a few points in a mini thread. 1: There is no chance in hell that people will develop "bioweapons" with your 23andMe data. youtube.com/watch?v=WbpwWH…

I'm excited to release what I've been cooking up the past few months at Arc Institute BINSEQ is a family of binary file formats for sequencing data built with paired records and parallel processing in mind with big performance gains (2x-40x) over gzip-fastq with similar storage

Very exciting. science.org/doi/10.1126/sc…