We’ve got holiday cheer on the brain. Happy holidays from your friends at Pyr

My latest #neuro #visualization: An intuition pump on connectivity in the #brain ~75K #neurons in the #MICrONS mm³. I/O segregated by layers, function is columnar; the cortical column is the unit of cortical computation. A typical #pyramidal cell has over >10K input #synapses.

One huge neuron! Layer 5 excitatory pyramidal

If you are good at programming / data analysis / algorithms and like challenges read on! FlyWire is issuing its first Data Challenge. We'll fly the winner to Princeton to give a talk about their solution🧵

Vampyramidal neurons. Happy Halloween! #neuroscience

Connectomics brings the brain into focus. Explore data from IARPA microns: microns-explorer.org

Wishing you a dazzling holiday season! Explore an interactive 3D pyramidal neuron from deep in visual cortex: microns-explorer.org/mm3/layer5_thi… Allen Institute IARPA Princeton Neuroscience Institute

🔥⚡ Action Potential: When neurons gossip ⚡🔥 "Hey, did you hear? Na+ rushed in, K+ stormed out, and BAM 💥 signal sent!" Sparking thoughts, moves, and feels. science.eyewire.org/neurons

inhibitory axon of the hippocampus

Coming soon: Hippocampal CA3 dataset

Request early access to a new Hippocampal Formation CA3 dataset -> pyr.ai

A few presynaptic axons connecting to a CA3 pyramidal neuron. Request early dataset access here: pyr.ai

>1,000 axons presynaptic to CA3 spiny pyramidal neurons have been proofread by citizen scientists. pyr.ai

A spiraling dance of neural threads, twisting, branching, in the head. A tangle born of thought and time, synapses spark and neurons climb. In crimson rivers, pathways stream, etching maps of hidden dreams. Image from CA3 by Nseraf

mossy fiber with several long filopodia request early access to Pyr CA3 dataset to unlock interactive 3D: play.pyr.ai/#!middleauth+h… pyr.ai/ca3_access

a little Picasso hidden in the dataset #em found by citizen scientist Krzysztof Kruk pyr.ai

Venture into the hippocampus: pyr.ai

A quick guide to 3D neuron navigation in neuroglancer: youtu.be/4Pi0QpjkDcI (try saying that 3 times fast) Explore interactive neurons from the microns dataset: microns-explorer.org/gallery-mm3

New preprint alert: hippocampus CA3! ∼1×1×0.1mm3 volume with 1,815 pyramidal neurons, 229 inhibitory cells, and 55,000 mossy fibers (like the ones shown below). Access the data at pyr.ai and explore the preprint below

The Institute for Advanced Study (Institute for Advanced Study (IAS)), the fabled home of Einstein and Gödel, announces a 2026-27 program on Modeling Fly Vision, intended to refound theor/comp neuro on the bedrock of 21st century brain maps. Apply for membership! ias.edu/sns/csb#specia…