Lewis Lab (@peterlewislab) 's Twitter Profile
Lewis Lab

@peterlewislab

Chromatin Biochemistry and Genomics Research Group
@UWMadison @UWSMPH @BMC_UW

ID: 1109193493606526976

linkhttp://TheLewisLab.net calendar_today22-03-2019 20:41:51

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Lewis Lab
@peterlewislab

8 months ago

Our collaboration with the Muir lab revealed that N-terminal histone modifications can 'detoxify' K27M inhibition by altering PRC2-substrate interactions. Acetylation showed the greatest impact, supported by xenograft data from the Monje group. pubs.acs.org/doi/epdf/10.10…

Our collaboration with the Muir lab revealed that N-terminal histone modifications can 'detoxify' K27M inhibition by altering PRC2-substrate interactions. Acetylation showed the greatest impact, supported by xenograft data from the Monje group. pubs.acs.org/doi/epdf/10.10…