I am excited to share our latest contribution to the RNA velocity field, which encapsulates a dedicated effort by my graduate student Alex Lederer to improve its statistical foundations and focus on its inferential value to ask scientific questions. 1/10 biorxiv.org/cgi/content/sh…

The Kampmann Lab at UC San Francisco is looking for staff research associates (technicians). Great opportunity to gain research experience for 2 years before applying to grad school! Supportive and diverse training environment. Please RT - thanks! Apply here: sjobs.brassring.com/TGnewUI/Search…

edgeR 4.0: powerful differential analysis of sequencing data with expanded functionality and improved support for small counts and ... biorxiv.org/cgi/content/sh… #biorxiv_bioinfo

1 in 8 women in the US will receive a breast cancer diagnosis in their life. Arc Investigator Hani Goodarzi led a TED Talks session on applying advanced AI and novel RNA molecules to detect+track breast cancer – changing the future of how cancer is screened bit.ly/3HCZpzx

.Sita Chandrasekaran and I are excited to share RESPLICE, a new RNA-programmable mode of editing that leverages RNA targeting CRISPR proteins and the endogenous spliceosomal machinery to enable versatile RNA edits in human cells! (1/12) biorxiv.org/content/10.110…

Have you ever wanted to profile how a molecular pathway affects neuronal activity, but didn't know where to start? I'm excited to share "A Massively Parallel CRISPR-Based Screening Platform for Modifiers of Neuronal Activity" 1/ biorxiv.org/content/10.110…

Chris Hsiung 熊 in the Gilbert Lab has developed an Acidaminococcus Cas12a variant that can knock down 3+ loci simultaneously – meaning researchers can study complex genetic interactions and map regulatory biology more effectively. Check it out: nature.com/articles/s4158…

Excited to see our work on human RNA switches published in Nature Methods today! nature.com/articles/s4159…

Today, we're shipping a series of features that move uv beyond a pip alternative, and into an end-to-end solution for managing Python projects, command-line tools, single-file scripts, and even Python itself. A single, unified tool. Like Cargo, for Python. It's very fast.