An exciting story and a wonderful collaboration! So happy to see it online Cancer Discovery! Many thanks and congrats to Prof. Hao Wu Melnick Lab Min Xia and all the team!

See the latest status on clinical trials and basic science: The 4th Inflammasome Therapeutics Summit will take place in Boston November 29 to December 1. Please join us! inflammasome-therapeutics.com

Another fun collaboration with Yarden Opatowsky team! #CryoEM Structure of a duplex of SARM1 octamers, an additional auto-inhibition mechanism that prevents pre-mature axon degeneration. Ben-Gurion University of the Negev Bar Ilan University link.springer.com/article/10.100…

Super excited to see our cool story on Piezo channels just published PNASNews Congrats to Prof. Hao Wu, Laurel Fuentes and all the team. A wonderful start for 2023! Happy Holidays!

Happy to share our story on NINJ1, NINJ2 and plasma membrane rupture. The NINJ1 part has a similar structure but different perspective on the mechanism compared to what was published two weeks ago by the Hiller Lab nature Stay tuned for a similar story from the Prof. Hao Wu .

So happy to share our #NINJ1 pre-print on Biorxiv reveling NINJ1 rings acting as cookie cutters to mediate plasma membrane rupture. Congrats to all authors Bobby Hollingsworth SteinbergLab Jazlyn Borges

Super excited to share our story published on GSDMD palmitoylation in Nature nature. Congrats to all the GSDMD team!

Now online! NINJ1 mediates plasma membrane rupture by cutting and releasing membrane disks dlvr.it/T5ZTlF

Published in Cell: #NINJ1 mediates plasma membrane rupture by cutting and releasing membrane disks. #MINFLUX imaging was used to confirm ring formation of endogenous NINJ1. cell.com/cell/abstract/… Great collaborative project from Prof. Hao Wu Liron David Bobby Hollingsworth

#NatMetabPicks | In nature led by Liron David and H. Wu (Ben-Gurion University of the Negev Harvard Medical School): Palmitoylation of Gasdermin D induces pore formation in pyroptosis. nature.com/articles/s4158…

At Cell we think immunology is for everyone, and we hope you'll check out our current issue: Focus on Immunology. I had a lot of fun working with the excellent authors who wrote these articles for our special #50YearsOfCell series! 🔬 Cell authors.elsevier.com/a/1i%7EWi_278y…

Our new spotlight on GSDMD Palmitoylation in Trends in Immunology very exciting new addition to “GSDMD-Cys191 ligands” Congrats to the authors on a beautiful study Liron David Prof. Hao Wu Jonathan Kagan

Amazing structure and beautiful work! Congrats to all the team 🎉

New preprint from our lab. Ryan Karimi 's program, Vesicle Picker, allows easy identification of vesicles and possible particle locations in cryoEM. The program uses cryosparc-tools to integrate Segment Anything (AI at Meta) with cryoSPARC (Structura Biotechnology). biorxiv.org/content/10.110…

מחפשים מעבדה לדוקטורט מעניין, מעשיר, מוצלח ומהנה? אנחנו מחפשים סטודנטים סקרנים ובעלי מוטיבציה להצטרף למעבדה החדשה שלנו שמתעסקת במחקר אימונולוגי של מחלות מדבקות. אנחנו מתעסקים במודלים עכבריים למחלות פרזיטיות, בתאי גזע של המעי והבקרה שלהם על-ידי מערכת החיסון. צרו קשר או רטרטו הלאה!