
Ioannis Vathiotis
@ivathiotis
Physician scientist | Medical Oncologist @uoaofficial Sotiria Hospital, Research Affiliate @YaleMed | Interested in #lungcancer #immunotherapy #biomarkers
ID: 849717342888185857
05-04-2017 20:16:16
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Research from Yale Cancer Center on a three-drug regimen in anti-PD-1-resistant #melanoma shows that higher doses were inferior to lower doses, and dose optimization is necessary for this patient population. Smilow Cancer Hospital Yale School of Medicine Yale New Haven Hosp Yale Pathology molecular-cancer.biomedcentral.com/articles/10.11…

In Annals of Oncology, Niki Gavrielatou Amanda Psyrri and coll. report #OpenAccess on a study evaluating biomarkers of patient outcome on PD-1-based immunotherapy in platinum-refractory head and neck squamous cell cancer annalsofoncology.org/article/S0923-… George Coukos @RimmPathology

#mdpijpm 💝Enjoy today's #Editor_Choice Paper "CD24: A Novel Target for Cancer Immunotherapy" 👥Emmanouil Panagiotou et al. University of Athens 👉More info: mdpi.com/1747790 MDPI MDPI Medicine & Pharmacology


"#Together we stand, divided we fall..." Thank you @myesmo, Raffaele Califano and all renowned speakers for this excellent preceptorship! Until next time! #lungcancer #collaboration #european #power #oncology #research #advances #TheChristieSoO #TheChristieNHS #oneteam #ESMO


New #JITC article: High-throughput transcriptome profiling indicates ribosomal RNAs to be associated with resistance to immunotherapy in non-small cell lung cancer (NSCLC) bit.ly/3RlgQdo Myrto K. Moutafi Thazin Nwe Aung, PhD @rolando_milian Ioannis Vathiotis Athanasios Angelakis



A new study from Dr. Thazin Nwe Aung Thazin Nwe Aung, PhD finds spatially-defined compartment signatures utilize tumor and tumor microenvironment-specific information, leading to more accurate prediction of treatment outcome in #melanoma. aacrjournals.org/clincancerres/… Smilow Cancer Hospital Yale School of Medicine Yale New Haven Hosp

Amazing Presidential Symposium ESMO - Eur. Oncology. Eyes to the future, biomarkers in the spotlight: precision oncology, AI, organ preservation approaches and emerging therapeutic targets. The future is bright - collaboration and access will be key!


Stage III ALK+ NSCLC: consolidation ALK TKI v Durva v Obs JTO & JTO CRR: -67pts, ALKi=15 Durva=30 obs=22 -mrwPFS favors ALKi (NR, 95%CI 22.7-NR) v durva (11.3m HR 0.12 p=0.006) v obs (7.2m HR=0.04 p<0.0001) Small n, but useful OncoAlert Amin Nassar, MD #LCSM jto.org/article/S1556-…



New test developed for #breastcancer by @RimmPathology at Yale School of Medicine may allow for more personalized #lungcancer therapy. “The way we did this measurement was by using cell line standards, which is a bit novel,” Dr. Rimm tells HemOnc Today. Yale Cancer Center bit.ly/3Z3FqU8


Phase I/II SOHO-01: BAY 2927088 in HER2m NSCLC. In HER2i-naive (cohort D): ORR 70.5%, DoR 8.7 mo. EGFRi-like AEs (rash, diarrhea). Busy Ph3 landscape: TKIS (SOHO-02, WU-KONG28 FURMO-004) or TKIs + ChT (REZILIENT3) vs SoC in 1L HER2m NSCLC #ESMOAmbassadors #ELCC25 ESMO - Eur. Oncology





Excited to share our review on "Molecular Landscape and Therapeutic Strategies of Lung Cancer Lineage Plasticity" in JTO & JTO CRR. We examine how #LUAD transforms into #SCLC or #LUSC under treatment pressure as a key factor in #resistance, and unpack the #genetic, #epigenetic,
