All you need to know about ANCA vasculitis. Epidemiology-Clinical Presentation- Pathophysiology, Diagnosis, Biomarkers, Management, QoL, Outlook, nature.com/articles/s4157… EULAR @ERAEDTA Int Society of Nephrology GlomCon RELENT project Nature Reviews Disease Primers

On kidney biopsy, the one-third of patients with membranous lupus nephritis who test positive for two proteins, exostosin 1 and 2, are less likely than EXT1/EXT2-negative patients to show biopsy findings signifying chronic disease or develop ESKD bit.ly/j2020081181

1/6 Good editorial discussion by Hans-Joachim Anders Marc Hilhorst on exostosin (EXT) in membranous lupus nephritis (LMN) based on our recent study: jasn.asnjournals.org/content/early/…

🆕Review: The podocyte as a direct target of glucocorticoids in nephrotic syndrome 📸Schematic overview of proposed molecules affected by glucocorticoid treatment 📖bit.ly/3pDQqDx👈 Nierstichting

March Highlights: Glomerular Exostosin Deposits in Membranous Lupus Nephritis—a Dialogue This editorial from Marc Hilhorst and Hans-Joachim Anders discusses advancements in knowledge of lupus nephritis kidney biopsies and their relationship with EXT1/EXT2 bit.ly/j2020121810

IgAN: Glomerular CD206+ macrophages predict response to steroids in the diagnostic biopsy jasn.asnjournals.org/content/early/… JASN_News Check also our editorial on how to select the right IgAN pts for costly immunotherapies Marc Hilhorst jasn.asnjournals.org/content/early/…

New Research: Gut Microbiota Dysbiosis in Systemic Lupus Erythematosus: Novel Insights into Mechanisms and Promising Therapeutic Strategies: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that was traditionally thought to… frontiersin.org/articles/10.33… #immunology

Innate immune response in the tubular system during trauma-related AKI. go.nature.com/31AyUWp

Thrilled to see my #mentor recognized at #Vasculitis22

Y. Vegting and Marc Hilhorst updated this 2012 meta-analysis (ELISA only, whereas Tomasson included also IIF for ANCA detection). While still suffering from heterogeneity, this study reinforces the idea that ANCA rises do precede relapses #Vasculitis22 2/x

Very cool and useful presentation by Mike Putman Sebastian E. Sattui MD, MS on the risk of PJP in GCA and PMR: Almost no case in this very large study, so prophylaxis does not seem necessary in this context #Vasculitis2022

ERA EDTA Paris! #ERA22

No salt for me sir ✋🚫 next generation ready to fight against hypertension and #CKD #KidneyWk #KidneySTARS #ASN2022