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#Etomidate and mortality in critically ill patients Etomidate is a common induction agent but controversy exists about its effects on outcomes Our meta-analysis found a high probability that etomidate increases mortality (NNH 31) 🧵Thread 1/6 🔗sciencedirect.com/science/articl… #FOAMcc

Giacomo Maiucci Gioia Piersanti @m_angelini_MS This study is clinically relevant. I am very reluctant to use eto. We have an accepted paper in J Intensive Care Med with COVID-19 patients with similar findings. It will be online within the next days. Unfortunately, many still believe that eto is a good induction agent.

Mubarak Alhatemi San Raffaele Anesthesia and Intensive Care Giovanni Landoni, MD 小谷祐樹 Yuki Kotani｜集中治療医 Intensivist Todd C. Lee Gioia Piersanti Giacomo Maiucci Stefano Turi JCriticalCare 𝙲𝚒𝚊𝚗𝙼𝚌𝙳𝚎𝚛𝚖𝚘𝚝𝚝 Sheila Myatra It’s not observational, it’s a meta-analysis of 12 RCTs. Sick people were *randomized* to etomidate vs something else. Those *randomized* to etomidate had more adrenal insufficiency & higher mortality.

Giacomo Maiucci Gioia Piersanti @m_angelini_MS It's available in 🇵🇱. It is quite frequently use for induction of unstable in the OR

🫀Hands-on session: invasive monitoring devices. Thanks Jacopo D’Andria Ursoleo, MD Fabrizio Monaco, MD San Raffaele Anesthesia and Intensive Care

Our new meta-analysis on #reparixin is out‼️ 🔹#mortality: 3.4% reparixin 6.4% controls 🔸risk of #pneumonia: trend toward reduction 🔹no difference in #sepsis and non-serious #infection ➡️ LIFE-SAVING AND SAFE Read more at: onlinelibrary.wiley.com/doi/10.1111/ec… #FOAMcc @IntensiveBot

Another promising treatment option for #COVID19 Our meta-analysis showed that antiandrogen drugs reduced mortality in COVID-19 They also prevented clinical worsening and hospitalization 🧵 will explain the details. 1/5 🔗 pubmed.ncbi.nlm.nih.gov/37204782/ #FOAMcc #MedTwitter

there are now 3 published sugroups of the ATHOS3 #rct with survival improvement when vasodilatory shock patients are randomized to #angiotensin II vs placebo on top of the best available treatment!! here is the main athos3 trial pubmed.ncbi.nlm.nih.gov/28528561/ published in NEJM

✅Summary of Important RCTs in ICU for the First Half of 2023! Quickly summarize the intensive care RCTs published from January to June this year! Specifically, 13 trials in NEJM, JAMA, and Lancet! I hope this 🧵 is a useful review of important literature👇👇 #FOAMcc

📰🗞️ Honoured to have had the possibility recently to be interviewed by Corriere della Sera to share views and insights on my life as an #anesthesiologist and #ICU specialist here at @SanRaffaeleMi and San Raffaele Anesthesia and Intensive Care Read the interview here:[milano.corriere.it/notizie/cronac…]

Does renin predict mortality in ICU & perioperative patients? A scoping review by 小谷祐樹 Yuki Kotani｜集中治療医 Intensivist Alessandro Belletti Giacomo Maiucci Lodovici M Stefano Fresilli Giovanni Landoni, MD Rinaldo Bellomo Alex Zarbock has summarized the available evidence👇 🔗 Anesthesia&Analgesia journals.lww.com/anesthesia-ana…

After performing this scoping review, I believe that renin is a promising prognostic marker among critically ill and perioperative patients and deserves further investigation! journals.lww.com/anesthesia-ana… #FOAMcc

Welcome to our new residents in Anesthesia and Intensive Care Medicine at Università Vita-Salute San Raffaele Ospedale San Raffaele! Wishing you a fulfilling and successful journey ahead.

Cool!! What about bringing this on Vision Pro Apple?

our etomidate article is the top cited and top ‘social’ 2023 JCriticalCare article! pubmed.ncbi.nlm.nih.gov/37127020/ 小谷祐樹 Yuki Kotani｜集中治療医 Intensivist Gioia Piersanti Giacomo Maiucci Stefano Fresilli Stefano Turi Todd C. Lee Giovanni Landoni, MD

Looking forward to see San Raffaele Anesthesia and Intensive Care at #CCR24 😍

小谷祐樹 Yuki Kotani｜集中治療医 Intensivist JCriticalCare Critical Care it is impressive that the ATS Blue Journal manuscript found an identical increase in mortality in critically ill pts receiving #etomidate compared to our previous JCriticalCare manuscript (RR 1.17 vs 1.16) Giacomo Maiucci Stefano Fresilli Stefano Turi Todd C. Lee San Raffaele Anesthesia and Intensive Care