MRD is highly prognostic in #AML and can inform SCT decisions or enrollment into MRD-directed clinical trials. MRD endpoints may also allow for accelerated drug approval in AML. New review by Nicholas Short MD and Richard Dillon in AmericanJournalofHematology doi.org/10.1002/ajh.27… #leusm

Today is the day 🤩. Thrilled to share our nature paper on Th2 function, CAR-T, & 8-year remission!⁩! Huge team effort w/⁦Stephan Grupp MD PhD⁩ ⁦⁦Carl June⁩ ⁦MelenhorstLab⁩ ⁦Li Tang⁩, kudos to my postdoc ⁦Zhiliang⁩ nature.com/articles/s4158…

Tefferi et al. describe a novel association between PHF6 mutations and superior prognosis in chronic myelomonocytic leukemia. The mutation was also associated with distinct phenotype including chronic thrombocytopenia and loss of Y chromosome #CMML #LeuSM onlinelibrary.wiley.com/doi/10.1002/aj…

Amazing day for the lab!

It's all about the methods! nature.com/articles/s4159…

Check out our newly published review Histopathology It was real fun to work with colleagues across the world Nikhil Patkar ACTREC-TMC Mayo Clinic Erasmus MC Molecular techniques in haematopathology: what and how? onlinelibrary.wiley.com/doi/full/10.11…

This is the first of the Annual Review Issue papers looking forward and collaboratively in #hempath. Thank you for your work! #

New Paper📢 WHO5 makes major changes to the B-ALL with entities defined by RNA sequencing and DNA based sequencing But it begs the question: Is the WHO5 applicable? Why do we need it? MRD trumps everything … right? What is the relevance in era of MRD directed therapy? 1/n

Big thanks to @RajpalShweta12 for leading this herculean task of completing this large dataset, Dr Gaurav Chatterjee and all members of the pediatric DMG. Chetan Dhamne , Nirmalya Roy Moulick Gaurav Narula MD, Shyam This is the link to the paper on MedRxiV. medrxiv.org/content/10.110…

Nikhil Patkar Gaurav Chatterjee Chetan Dhamne Gaurav Narula MD Thrilled to share the results of our B-ALL study! Huge thanks to Nikhil Patkar , Gaurav Chatterjee , Pgs_mani , Prashant Tembhare , and Dr. Sumeet Gujral for being my guiding light.

This paper is special for us Painstakingly gathered data on the back of #ICiCLe2014 trial We looked at molecular profiles on behavior of Pediatric B-ALL & came up with profiles- some known ones & a few surprises! PHO INDIA Pediatric Hematology Oncology Journal Venky Scott Howard, MD, MSc The World SIOP Chetan Dhamne

This took a lot of work. So happy to see it uploaded finally! Big congratulations to Sweta Rajpal. Here's to many more such data from our lab in future!

Tata Bye Bye Flow, FISH and Cytogenetics for ALL diagnosis. Nanopore technology is here, one stop test for diagnosis and risk stratification. #SIOPCongress #SIOPambassador

Today, we announced the first #PacBio benchtop long-read sequencing system, Vega. #Vega delivers all the functionality of #Revio into a compact, lower- throughput benchtop platform. bit.ly/3O0mP5b #ASHG24 #ASHG2024

They da BEST ! Mayur Nikhil Patkar Tata Medical Center ACTREC-TMC Our hemepath community is filled with rockstars!✨ Cc: Prof. Dr Anil Handoo Prof. Prashant Tembhare Thulasi Raman Karthik Bommannan Vishvdeep Khushoo Lingaraj Nayak Gurleen Oberoi #haematocon2024nagpur ☕️ 🔬 🩸 🧬🧫🧪🩺👀

Gaurav Chatterjee Sumeet Mirgh MD, DM Nikita Mehra Mayur Tata Medical Center ACTREC-TMC Dr Anil Handoo Prashant Tembhare Thulasi Raman Karthik Bommannan Vishvdeep Khushoo Lingaraj Nayak Gurleen Oberoi Sweta Rajpal Terry Muskoff Anant Gokarn Soooooo much to do. Miles to go. All over discussion and some ☕

🧬🔍There are 50 petabases of freely-available DNA sequencing data. We introduce "Logan Search" which allows you to search for any DNA sequence in minutes, bringing Earth’s largest genomic resource to your fingertips. 🏔️ logan-search.org 🏔️ #Genomics #Bioinformatics 🧵👇

Real-world impact of differences in the WHO and ICC classifications of non-Hodgkin lymphoma: a LEO cohort study analysis ow.ly/p4Bt50U2zcE #lymphoidneoplasia

Had a wonderful and eventful weekend organizing and hosting #SpectrumIndia2024, the landmark Interventional Oncology conference. It couldn’t get better that this.. Spectrumindia2024 Tata Memorial Hospital @SIO @ MVF

A new Science study presents “Evo”—a machine learning model capable of decoding and designing DNA, RNA, and protein sequences, from molecular to genome scale, with unparalleled accuracy. Evo’s ability to predict, generate, and engineer entire genomic sequences could change the