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Good morning Chicago! Happy ASCO Hump Day #3, everyone! #ASCO25

3rd NEJM publication for #bcsm at #ASCO25 in the last 2 days (that I'm aware of!). #camizestrant #ESR1 Come to plenary Hall B1 today at 1pm to hear the presentation by Dr. Turner and discussion about potential impact by Angie DeMichele, MD, MSCE, FASCO! nejm.org/doi/full/10.10…

Honored to celebrate mentor and Sarah Cannon Docs President Skip Burris, MD on this well-deserved recognition. His leadership has shaped generations of oncology researchers—including me. Congratulations, Skip!

I am loving Dr. DeMichele’s comments, including her insistence on longer survival and discussion of crossover issues. #ASCO25 #plenary #serena-6 Also loving audience questions. They are asking hard questions on the utility of PFS. I feel happy that the education is spreading and

Insights to Impact by Mark Lewis, MD, FASCO (oncologists + patient) perspective: Knowledge to Action!! What should be at the center of our discussion: - Respecting pt autonomy - Time and financial toxicity - Longevity and Quality #OncTwitter #MedTwitter

Good Morning, #ASCO25. You’ve made it to day 4. Your feet may be tired, but your hearts and brains are full. So many great sessions to come.. but also summer has finally come to Chicago so make it to the ASCO Garden for a little sunshine

Wow, right? 7:30 Monday at #ASCO25. Agree! No doubt #DB09 will be practice changing. The question is, how will we handle maintenance?

Particularly excited about the activity in #TNBC post topo-1 ADCs. 86% had seen savituzumab govitecan, 1/3 had seen T-DXd, 1/4 had seen both! #ASCO25 #ADC #NewTargetNewPayload

Very exciting!!! We need new drugs especially in mTNBC and especially post topo-1 ADCs as they move further up in our treatment paradigm

NeoCARHP: de-escalated HER-2 neoadj thpy for #bcsm 🤩THP non inferior to TCHP in pCR, both HR+ and HR- HER-2+ disease 😅 phew, I'd already been doing this for some older pts 🩸 G3/4 neutropenia ⬇️ by 10% w/ THP Interestingly, neuropathy not different #ASCO25

Multiple studies looking at neoadjuvant regimens for HER2+ early BC. Looks like THP would suffice for most stage 1 and 2, and Cb not needed. Interesting question as to whether 6 cycles / 18 weeks is > than 4 cycles / 12 weeks. ASCO #ASCO25 OncoAlert

Not suprising, this is as we thought, but amazing that it was formally tested and done. Sorry..scalp cooling does not work for T-DXd and I would extrapolate to other #ADCs with long half lives. #hairloss #bcsm #ASCO25 #scalpcooling

#SOFT and #TEXT looking at AI vs. tam and OFS vs. not, 15 yr f/u 📌Adding OFS gives you 3.7% ⬆️ DFS 📌OFS + AI gets you 6.5% ⬆️ DFS 📍OFS + AI improves gives you ⬆️ 4.3% OS 🌟 Ultra young <35, it's even more important #ASCO25 #bcsm

Completely agree. Many women make the choice to receive chemo for a benefit less than this. It's HUGE! Ovarian suppression and AI is a powerful tool to decrease recurrences.

Maybe I'm delirious at this point Mon pm at #ASCO25. But I just made myself LOL at McCormick Uber pick up thinking about the study reporting whether the attendants yelling & blowing whistles to "keep moving" does anything to make the cars move faster. Hall B1, predict HR 1.0

Small glimpse of *part* of my tribe- a couple of the Sarah Cannon Docs crew that so amazingly supports us in every way. My EA Lisa, our #bcsm program manager Mythili, our President and my mentor Skip Burris, MD, and of course our CEO Dee Anna Smith (and soon to be Sarah Premji, MD).

🔥📣The 2025 #ASCOEdBook collection from ASCO #ASCO25 is now complete & fully available (for free). ✅It’s a great resource with very EDUCATIONAL peer-reviewed articles by great experts. Outstanding job by editors & authors.👏 Link to full edition👇🏻 bit.ly/44bvEkk

#HongKong Amazing time with the chair, Dr. Rina Hui, at Hong Kong International Oncology Forum 2025. Great meeting, fantastic hospitality! Btw...Paolo Tarantino self game on #internationalselfieday is strong 💪🏼