Steroids remain the most widely prescribed drug for IBD around the world - for short-term symptom control Should NOT be used for long-term maintenance Very interesting recommendations from colleagues European Society of Endocrinology (ESE) on short-term prescribing Thoughts from IBD colleagues? 🤔🌍

I’m very happy and proud to announce the publication of my debut as co-first-author research article in Nature Immunology ! 🎉 we revealed a distinct serum ASCA IgG glycoform able to predict the development of Crohn’s Salome Pinho Joana Gaifem i3S-Instituto de Investigação e Inovação em Saúde nature.com/articles/s4159…

🚀 Exciting study alert ‼️ ✅a novel PCM-CT technique using single-clip traction for endoscopic submucosal dissection. 🔬✨ 📙tinyurl.com/5cbsu642 #GITwitter #LiverTwitter #MedTwitter #MedEd ESGE ASGE GI Endoscopy my_UEG ACG American Gastroenterological Association (AGA)

Jest coraz lepiej w zakresie jakości opieki nad Pacjentami z NIESWOISTYMI CHOROBAMI ZAPALNYMI JELIT w 🇵🇱, ale nadal jest i będzie sporo do zrobienia Puls Medycyny Ministerstwo Zdrowia Iza Leszczyna✌️🇵🇱 Żaneta Cwalina - Śliwowska #IBD #GITwitter Y-ECCO

Dual biological therapy shows promise for treating children with severe, refractory #IBD. ✅ 45% achieved clinical remission within 12 months, offering a potential alternative for those failing previous treatments. #Pediatrics #Gastroenterology onlinelibrary.wiley.com/doi/10.1002/jp…

RCTs = 🔑 to medicine. But…cost lots of 💰 + take loads of ⏳ Good + short 💭 on possibly better trials Gastroenterology American Gastroenterological Association (AGA) 🟢Basket trials 🟢Umbrella trials 🟢Platform trials ⏺️GI fellows - ✅this and deepen your understanding gastrojournal.org/action/showPdf…

Important data from PODCAST study🔊 Proportion of patients with inflammatory bowel disease with suboptimal disease control in daily clinical practice🔥 52% Crohn's disease & 44% ulcerative colitis👥 LOTS of room for improvement in monitoring & treatment onlinelibrary.wiley.com/doi/10.1002/ue…

Emerging role of environmental pollutants in inflammatory bowel disease risk, outcomes and underlying mechanisms. pubmed.ncbi.nlm.nih.gov/39179372/

How to combine FIB-4 and Elastography to screen for liver fibrosis ? Which algorithms are proposed by the main liver/GI societies ? I find this summarizing figure very useful. t.ly/V6cvF

🆕 How do you manage patients with positive coeliac serology but normal biopsies? 🤔 Our latest study in Gut Journal shows that nearly 1 in 3 patients with PCD progress to villous atrophy, while most symptomatic patients improve on a gluten-free diet. bit.ly/46T8JLx

Intensified versus standard dose infliximab induction therapy for steroid-refractory acute severe ulcerative colitis (PREDICT-UC): an open-label, multicentre, randomised controlled trial The Lancet Gastroenterology & Hepatology thelancet.com/journals/langa…

📢 New guidelines on #MASLD (formerly #NAFLD)🔥 🔗📘tinyurl.com/scwnk6m6 ✅emphasize lifestyle changes & careful screening for liver fibrosis, especially in those with #diabetes or #obesity. 🩺 #GitTwitter #MedEd #LiverTwitter #MetabolicSyndrome #myUEGcommunity

Guidelines recommend early initiation of advanced therapy (AT) for mod-severe IBD, are we following them? 📋 We can do better according to recent study by Corey Siegel ⛔️ Only 14% of pts with CD and 6% of pts with UC had AT during 2 yr follow up academic.oup.com/crohnscolitis3…

Several stakeholders have advocated for minimising placebo controlled RCTs. We analysed the harms [Adverse Events,[AEs]] associated with placebo in inflammatory bowel diseases (IBD) RCTs. Alexander Ford Beatriz Gros Jonathan Segal Jonny Blackwell Chris Black Luminal Gastroenterology Research Leeds